Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.48 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 4/20 | 0.38 |
| ▸ | MAOA | P21397 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8619850 | 0.82 | LOXL2 (0.36) | LOXL2CYP2A6IDO1ALDH1A1MAOB | |
| SCHEMBL8616932 | 0.76 | GRM5 (0.40) | FFAR1 | |
| SCHEMBL28224573 | 0.75 | LOXL2 (0.48) | LOXL2CYP2A6IDO1ALDH1A1MAOB | |
| SCHEMBL8623109 | 0.75 | CA12 (0.36) | LOXL2CYP2A6FFAR1MAOB | |
| SCHEMBL28743584 | 0.75 | LOXL2 (0.48) | LOXL2CYP2A6IDO1ALDH1A1MAOB | |
| SCHEMBL8516827 | 0.75 | LOXL2 (0.48) | LOXL2CYP2A6IDO1ALDH1A1MAOB | |
| SCHEMBL8516828 | 0.75 | LOXL2 (0.48) | LOXL2CYP2A6IDO1ALDH1A1MAOB | |
| SCHEMBL8622284 | 0.74 | PTGES2 (0.41) | ALDH1A1L3MBTL1HTTTSHR | |
| SCHEMBL17855518 | 0.73 | LOXL2 (0.47) | LOXL2CYP2A6IDO1ALDH1A1MAOB | |
| SCHEMBL10671045 | 0.73 | LOXL2 (0.47) | LOXL2CYP2A6IDO1ALDH1A1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0648723-B1 | Diphenylacetylene compound, process for preparing the same and liquid crystal composition and element comprising the same | SUMITOMO CHEMICAL CO (JP) | 1998-05-20 | — | — | EP | disclosed |
| US-5658489-A | EXCELLENT ANISOTROPY OF REFRACTIVE INDEX; LOW VISCOSITY | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-08-19 | — | — | US | disclosed |
| EP-0648723-A1 | Diphenylacetylene compound, process for preparing the same and liquid crystal composition and element comprising the same | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1995-04-19 | — | — | EP | disclosed |