Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 13/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8614769 | 0.88 | DHODH (0.45) | ACP1ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL8617830 | 0.88 | ACP1 (0.46) | ACP1ALDH1A1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL8614778 | 0.85 | ACP1 (0.43) | ACP1ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL8618615 | 0.84 | ALDH1A1 (0.46) | ACP1ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL8616988 | 0.82 | KMT2A (0.47) | ACP1ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL8617128 | 0.81 | ACP1 (0.35) | ACP1ALDH1A1KDM4EHTTMEN1 | |
| SCHEMBL8614857 | 0.81 | ABCB1 (0.55) | ACP1ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL8618628 | 0.80 | ALDH1A1 (0.47) | ACP1ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL8618001 | 0.79 | DHODH (0.46) | ACP1ALDH1A1DHODHMEN1KMT2A | |
| SCHEMBL8617119 | 0.78 | ABCB1 (0.45) | ACP1ALDH1A1KDM4ELMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0726254-B1 | Quinoline-4-carbonylguanidine derivates, process for producing the same and pharmaceutical preparations containing the compounds | MITSUI TOATSU CHEMICALS (JP) | 1998-05-06 | — | — | EP | disclosed |
| US-5627193-A | MEDICAL DIAGNOSIS, CARDIOVASCULAR DIAORDERS AND PROTECTION OF ORGANS FOR TRANSPLANTATION | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-05-06 | — | — | US | disclosed |
| EP-0726254-A1 | Quinoline-4-carbonylguanidine derivates, process for producing the same and pharmaceutical preparations containing the compounds | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-08-14 | — | — | EP | disclosed |