Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 13/20 | 1.00 |
| ▸ | MEN1 | O00255 | 10/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 10/20 | 1.00 |
| ▸ | TP53 | P04637 | 9/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 6/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.76 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.76 |
| ▸ | HPGD | P15428 | 6/20 | 0.76 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.76 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.76 |
| ▸ | GAA | P10253 | 2/20 | 0.76 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.76 |
| ▸ | NPC1 | O15118 | 1/20 | 0.73 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.73 |
| ▸ | RAB9A | P51151 | 1/20 | 0.73 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.73 |
| ▸ | RELA | Q04206 | 1/20 | 0.73 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.73 |
| ▸ | RAF1 | P04049 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL861728 | 1.00 | MAPT (1.00) | MAPTMEN1KMT2ATP53MAPK1 | |
| SCHEMBL13394658 | 0.88 | MAPT (0.79) | MAPTMEN1KMT2ATP53MAPK1 | |
| SCHEMBL11471577 | 0.87 | MAPT (0.77) | MAPTMEN1KMT2ATP53MAPK1 | |
| SCHEMBL9420982 | 0.86 | MAPT (1.00) | MAPTMEN1KMT2ATP53MAPK1 | |
| SCHEMBL8806771 | 0.86 | MAPT (0.76) | MAPTMEN1KMT2ATP53MAPK1 | |
| SCHEMBL8806767 | 0.86 | MAPT (0.76) | MAPTMEN1KMT2ATP53MAPK1 | |
| SCHEMBL1566918 | 0.85 | MAPT (0.74) | MAPTMEN1KMT2ATP53MAPK1 | |
| SCHEMBL16296742 | 0.85 | MAPT (0.74) | MAPTMEN1KMT2ATP53MAPK1 | |
| SCHEMBL1566916 | 0.85 | MAPT (0.74) | MAPTMEN1KMT2ATP53MAPK1 | |
| SCHEMBL12162614 | 0.85 | MAPT (1.00) | MAPTMEN1KMT2ATP53MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107365986-B | A kind of chemical tin inorganic agent and the tin plating technique using the chemical tin inorganic agent | 东莞市富默克化工有限公司 | 2019-08-09 | — | — | CN | claimed |
| CN-107365986-A | A kind of tin plating technique of chemical tin inorganic agent and application the chemical tin inorganic agent | 东莞市富默克化工有限公司 | 2017-11-21 | — | — | CN | claimed |
| WO-2005121129-A1 | NOVEL PROPENONE DERIVATIVES CONTAINING AROMATIC RINGS, A MAUFACTURING PROCESS THEREOF AND A COMPOSITION CONTAINING THE SAME USING AS AN ANTIINFLAMMATORY AGENT | YEUNGNAM EDUCATIONAL FOUNDATION (KR) | 2005-12-22 | — | — | WO | claimed |
| US-20260007642-A1 | INHIBITORS OF SHORT-CHAIN DEHYDROGENASE ACTIVITY FOR PROMOTING NEUROGENESIS AND INHIBITING NERVE CELL DEATH | UNIV CASE WESTERN RESERVE (US) | 2026-01-08 | — | — | US | disclosed |
| EP-3267995-B1 | INHIBITORS OF SHORT-CHAIN DEHYDROGENASE ACTIVITY FOR TREATING FIBROSIS | UNIV CASE WESTERN RESERVE (US) | 2025-10-08 | — | — | EP | disclosed |
| US-20250304597-A1 | COMPOSITIONS AND METHODS OF MODULATING SHORT-CHAIN DEHYDROGENASE ACTIVITY | BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM | 2025-10-02 | — | — | US | disclosed |
| US-20250295640-A1 | INHIBITORS OF SHORT-CHAIN DEHYDROGENASE ACTIVITY FOR TREATING FIBROSIS | CASE WESTERN RESERVE UNIVERSITY | 2025-09-25 | — | — | US | disclosed |
| US-20240368001-A1 | SALT RECOVERY SOLUTION AND PROCESSES OF USE THEREOF | AQUAFORTUS TECHNOLOGIES LIMITED (NZ) | 2024-11-07 | — | — | US | disclosed |
| US-11987506-B2 | Salt recovery solution and processes of use thereof | AQUAFORTUS TECHNOLOGIES LIMITED (NZ) | 2024-05-21 | — | — | US | disclosed |
| CN-114524829-B | Preparation method of imidazo [2,1-b ] thiazole derivative | 新疆大学 | 2024-04-02 | — | — | CN | disclosed |
| US-20240100026-A1 | INHIBITORS OF SHORT-CHAIN DEHYDROGENASE ACTIVITY FOR PROMOTING NEUROGENESIS AND INHIBITING NERVE CELL DEATH | UNIVERSITY OF IOWA RESEARCH FOUNDATION | 2024-03-28 | — | — | US | disclosed |
| US-20080261953-A1 | Compounds, Compositions and Methods of Inhibiting Alpha-Synuclein Toxicity | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2008-10-23 | — | — | US | disclosed |
| EP-1802303-A2 | COMPOUNDS, COMPOSITIONS AND METHODS OF INHIBITING A-SYNUCLEIN TOXICITY | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2007-07-04 | — | — | EP | disclosed |
| WO-2006034003-A2 | COMPOUNDS, COMPOSITIONS AND METHODS OF INHIBITING A-SYNUCLEIN TOXICITY | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2006-03-30 | — | — | WO | disclosed |
| WO-2005121129-A1 | NOVEL PROPENONE DERIVATIVES CONTAINING AROMATIC RINGS, A MAUFACTURING PROCESS THEREOF AND A COMPOSITION CONTAINING THE SAME USING AS AN ANTIINFLAMMATORY AGENT | YEUNGNAM EDUCATIONAL FOUNDATION (KR) | 2005-12-22 | — | — | WO | disclosed |
| EP-0333591-B1 | Process for formation of resist patterns | FUJITSU LTD (JP) | 1997-10-29 | — | — | EP | disclosed |
| US-5492915-A | ANTIINFLAMMATORY AGENTS | RHONE-POULENC RORER S.A. (FR) | 1996-02-20 | — | — | US | disclosed |
| US-5366982-A | Antiinflammatory agents or antihistamines | RHONE-POULENC RORER S.A. (FR) | 1994-11-22 | — | — | US | disclosed |
| US-5194364-A | Polymers from silane substituted acetylenes | FUJITSU LIMITED (JP) | 1993-03-16 | — | — | US | disclosed |
| EP-0333591-A2 | Process for formation of resist patterns | FUJITSU LIMITED (JP) | 1989-09-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080261953-A1 | Compounds, Compositions and Methods of Inhibiting Alpha-Synuclein Toxicity | SNCA, PARK7, HTT | MAPT 30/4885MEN1 4741/4885KMT2A 1570/4885 |
| US-20250304597-A1 | COMPOSITIONS AND METHODS OF MODULATING SHORT-CHAIN DEHYDROGENASE ACTIVITY | HPGD, GCDH, HPGDS | MAPT 4066/4885MEN1 4461/4885KMT2A 3903/4885 |
| US-20240100026-A1 | INHIBITORS OF SHORT-CHAIN DEHYDROGENASE ACTIVITY FOR PROMOTING NEUROGENESIS AND INHIBITING NERVE CELL DEATH | HPGD, GCDH, DCX | MAPT 1464/4885MEN1 4843/4885KMT2A 3226/4885 |
| US-20250295640-A1 | INHIBITORS OF SHORT-CHAIN DEHYDROGENASE ACTIVITY FOR TREATING FIBROSIS | GCDH, HPGD, UGDH | MAPT 4398/4885MEN1 4619/4885KMT2A 3603/4885 |
| US-20260007642-A1 | INHIBITORS OF SHORT-CHAIN DEHYDROGENASE ACTIVITY FOR PROMOTING NEUROGENESIS AND INHIBITING NERVE CELL DEATH | PTGDR, HPGD, PTGDR2 | MAPT 1021/4885MEN1 4874/4885KMT2A 3082/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.