Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | LCK | P06239 | 1/20 | 0.48 |
| ▸ | PPARD | Q03181 | 1/20 | 0.48 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.48 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.43 |
| ▸ | GMNN | O75496 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17627568 | 1.00 | GPR84 (0.55) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL8619966 | 0.92 | CA2 (0.45) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL8362469 | 0.91 | GPR84 (0.53) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL9339334 | 0.91 | GPR84 (0.53) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL28846006 | 0.91 | GPR84 (0.53) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL5054302 | 0.90 | GPR84 (0.61) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL11806278 | 0.90 | GPR84 (0.61) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL8917383 | 0.90 | GPR84 (0.61) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL21679654 | 0.90 | GPR84 (0.61) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL159858 | 0.90 | GPR84 (0.61) | GPR84FFAR1MAPTLCKPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3765024-A1 | NOVEL PHARMACEUTICAL FORMULATION COMPRISING DUAL NK-1/NK-3 RECEPTOR ANTAGONISTS | KaNDy Therapeutics Limited (GB) | 2021-01-20 | — | — | EP | disclosed |
| WO-2019175253-A1 | NOVEL PHARMACEUTICAL FORMULATION COMPRISING DUAL NK-1/NK-3 RECEPTOR ANTAGONISTS | KaNDy Therapeutics Limited (GB) | 2019-09-19 | — | — | WO | disclosed |
| US-5760022-A | ESTER, ETHER | PERSTORP AB (SE) | 1998-06-02 | — | — | US | disclosed |
| EP-0797443-A1 | A PHARMACEUTICAL COMPOSITION WITH IMPROVED BIO-AVAILABILITY OF INOSITOL PHOSPHATE | PERSTORP AB (SE) | 1997-10-01 | — | — | EP | disclosed |
| WO-1995019775-A1 | A PHARMACEUTICAL COMPOSITION WITH IMPROVED BIO-AVAILABILITY OF INOSITOL PHOSPHATE | PERSTORP AB (SE) | 1995-07-27 | — | — | WO | disclosed |