Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | QPCT | Q16769 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 5/20 | 0.39 |
| ▸ | KIT | P10721 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HTR1D | P28221 | 2/20 | 0.36 |
| ▸ | HTR1B | P28222 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8590953 | 0.82 | MAPT (0.50) | HRH3MCHR1QPCTRAB9AKDR | |
| SCHEMBL8590964 | 0.82 | HRH3 (0.51) | HRH3RAB9AKDRMAPTKDM4E | |
| SCHEMBL8590131 | 0.81 | MCHR1 (0.53) | HRH3MCHR1KDRKITFLT3 | |
| SCHEMBL8589629 | 0.79 | HRH3 (0.50) | HRH3MCHR1QPCTRAB9AKDR | |
| SCHEMBL8589733 | 0.79 | HRH3 (0.70) | HRH3MCHR1QPCTRAB9AKDR | |
| SCHEMBL8617490 | 0.78 | HRH3 (0.49) | HRH3MCHR1QPCTRAB9AKDR | |
| SCHEMBL6541884 | 0.78 | MCHR1 (0.48) | HRH3MCHR1QPCTKDRMAPT | |
| SCHEMBL8589432 | 0.78 | ALDH1A1 (0.51) | HRH3MCHR1RAB9AKDRMAPT | |
| SCHEMBL8589856 | 0.77 | HTR1D (0.47) | HRH3MCHR1QPCTKDRKIT | |
| SCHEMBL8587504 | 0.77 | HRH3 (0.53) | HRH3MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998050346-A2 | ACETAMIDE AND UREA DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THE TREATMENT OF CNS DISORDERS | SMITHKLINE BEECHAM PLC (GB) | 1998-11-12 | — | — | WO | disclosed |