Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.70 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | DDX3X | O00571 | 1/20 | 0.43 |
| ▸ | IDH1 | O75874 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 4/20 | 0.42 |
| ▸ | KIT | P10721 | 1/20 | 0.42 |
| ▸ | FLT3 | P36888 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TOP1 | P11387 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | QPCT | Q16769 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8590451 | 0.90 | HRH3 (0.56) | HRH3RXFP1KDRNPC1MAPT | |
| SCHEMBL8589516 | 0.84 | MEN1 (0.53) | HRH3RXFP1MCHR1KDRNPC1 | |
| SCHEMBL8587717 | 0.84 | RAB9A (0.53) | HRH3RXFP1NPC1MAPTRAB9A | |
| SCHEMBL8590131 | 0.83 | MCHR1 (0.53) | HRH3RXFP1MCHR1KDRKIT | |
| SCHEMBL8590953 | 0.82 | MAPT (0.50) | HRH3IDH1MCHR1KDRKIT | |
| SCHEMBL8590964 | 0.82 | HRH3 (0.51) | HRH3KDRNPC1MAPTRAB9A | |
| SCHEMBL8589432 | 0.82 | ALDH1A1 (0.51) | HRH3MCHR1KDRNPC1MAPT | |
| SCHEMBL8589512 | 0.82 | ALDH1A1 (0.52) | HRH3RXFP1DDX3XMCHR1NPC1 | |
| SCHEMBL8619358 | 0.81 | MAPT (0.47) | HRH3RXFP1IDH1MCHR1KDR | |
| SCHEMBL8590190 | 0.81 | KMT2A (0.47) | HRH3RXFP1MCHR1KDRNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998050346-A2 | ACETAMIDE AND UREA DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THE TREATMENT OF CNS DISORDERS | SMITHKLINE BEECHAM PLC (GB) | 1998-11-12 | — | — | WO | disclosed |