SCHEMBL8617477

SCHEMBL8617477

COC(=O)c1cccc(OC(=O)NC2C(=O)N(CC34CC5CC(CC(C5)C3)C4)c3ccccc3N(c3ccccc3)C2=O)c1

nearest known ligand 0.65

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CCKBR P32239 20/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8621832 0.94 CCKBR (0.72) CCKBR
SCHEMBL9014086 0.90 CCKBR (0.75) CCKBR
SCHEMBL8618848 0.87 CCKBR (0.79) CCKBR
SCHEMBL9014072 0.83 CCKBR (0.65) CCKBR
SCHEMBL8635124 0.82 CCKBR (0.73) CCKBR
SCHEMBL8619092 0.80 CCKBR (0.70) CCKBR
SCHEMBL8617223 0.80 CCKBR (0.74) CCKBR
SCHEMBL8638672 0.80 CCKBR (0.81) CCKBR
SCHEMBL8637453 0.79 CCKBR (1.00) CCKBR
SCHEMBL8635663 0.78 CCKBR (1.00) CCKBR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0623118-B1 CARBAMATE DERIVATIVES AND THEIR USE IN MEDICINE GLAXO WELLCOME SPA (IT) 1998-05-13 EP disclosed
US-5486514-A GASTRIN, CHOLECYSTOKININ RECEPTOR ANTAGONISTS GLAXO SPA (IT) 1996-01-23 US disclosed