Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 20/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9014086 | 0.91 | CCKBR (0.75) | CCKBR | |
| SCHEMBL8617223 | 0.90 | CCKBR (0.74) | CCKBR | |
| SCHEMBL8621832 | 0.85 | CCKBR (0.72) | CCKBR | |
| SCHEMBL8615099 | 0.84 | CCKBR (0.56) | CCKBR | |
| Dimethylamine SCHEMBL8638834 | 0.82 | CCKBR (0.94) | CCKBR | |
| SCHEMBL8618848 | 0.82 | CCKBR (0.79) | CCKBR | |
| SCHEMBL8617477 | 0.82 | CCKBR (0.65) | CCKBR | |
| SCHEMBL8618163 | 0.82 | CCKBR (0.70) | CCKBR | |
| SCHEMBL9014072 | 0.82 | CCKBR (0.65) | CCKBR | |
| SCHEMBL8622444 | 0.82 | CCKBR (0.73) | CCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0558104-B1 | 1,5-Benzodiazepine derivatives and their use in medicine | GLAXO WELLCOME SPA (IT) | 1998-07-29 | — | — | EP | disclosed |
| US-5763436-A | ANTICOAGULANTS | HOFFMANN-LA ROCHE INC. (US) | 1998-06-09 | — | — | US | disclosed |
| US-5637697-A | ANTAGONIST TO GASTRIN AND(OR) CHLOROCYSTOKININ | GLAXO SPA (IT) | 1997-06-10 | — | — | US | disclosed |
| US-5580895-A | GASTROINTESTINAL OR CENTRAL NERVOUS SYSTEM DISORDERS | GLAXO SPA (IT) | 1996-12-03 | — | — | US | disclosed |
| EP-0558104-A1 | 1,5-Benzodiazepine derivatives and their use in medicine | GLAXO S.p.A. (IT) | 1993-09-01 | — | — | EP | disclosed |