Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.38 |
| ▸ | S100A4 | P26447 | 1/20 | 0.38 |
| ▸ | EDNRB | P24530 | 2/20 | 0.38 |
| ▸ | EDNRA | P25101 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | PTPRC | P08575 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31650648 | 1.00 | PBRM1 (0.44) | PBRM1CYP1A2MAPK1SRD5A1S100A4 | |
| SCHEMBL30917701 | 1.00 | PBRM1 (0.44) | PBRM1CYP1A2MAPK1SRD5A1S100A4 | |
| SCHEMBL30917697 | 1.00 | PBRM1 (0.44) | PBRM1CYP1A2MAPK1SRD5A1S100A4 | |
| Aluminum Chloride Anhydrous SCHEMBL30917821 | 0.94 | PBRM1 (0.40) | PBRM1CYP1A2MAPK1SRD5A1S100A4 | |
| Aluminum Chloride Anhydrous SCHEMBL31737384 | 0.94 | PBRM1 (0.40) | PBRM1CYP1A2MAPK1SRD5A1S100A4 | |
| SCHEMBL14169119 | 0.82 | PBRM1 (0.54) | PBRM1CYP1A2MAPK1S100A4EDNRB | |
| SCHEMBL26656332 | 0.82 | PBRM1 (0.54) | PBRM1CYP1A2MAPK1S100A4EDNRB | |
| SCHEMBL13383481 | 0.81 | ACHE (0.46) | SRD5A1PARP10PARP1CA1CA2 | |
| SCHEMBL28045673 | 0.81 | ACHE (0.46) | SRD5A1PARP10PARP1CA1CA2 | |
| SCHEMBL31650145 | 0.80 | PBRM1 (0.39) | PBRM1CYP1A2MAPK1SRD5A1S100A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753655-A | PROGESTINS OR ANTIPROGESTINS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-05-19 | — | — | US | disclosed |
| WO-1997017332-A1 | 1-ARYLSULPHONYL, ARYL(THIO)CARBONYL PYRIDAZINO DERIVATIVES AND METHODS OF PREPARATION | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-05-15 | — | — | WO | disclosed |