SCHEMBL28045673

SCHEMBL28045673

Cc1ccc2c(c1)C(=O)CC[C@H]2C

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.46
SRD5A1 P18405 4/20 0.38
PARP10 Q53GL7 2/20 0.38
PARP1 P09874 1/20 0.38
MAOB P27338 3/20 0.37
MAOA P21397 1/20 0.37
ELANE P08246 1/20 0.36
ATM Q13315 2/20 0.36
KDM4E B2RXH2 1/20 0.36
HTT P42858 1/20 0.36
METAP1 P53582 1/20 0.35
CA1 P00915 2/20 0.35
CA2 P00918 2/20 0.35
CA4 P22748 1/20 0.34
CA7 P43166 1/20 0.34
CA9 Q16790 1/20 0.34
PARP11 Q9NR21 1/20 0.34
ALDH1A1 P00352 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13383481 1.00 ACHE (0.46) ACHESRD5A1PARP10PARP1MAOB
SCHEMBL16692285 0.86 SRD5A1 (0.44) ACHESRD5A1PARP10PARP1MAOB
SCHEMBL30917701 0.81 PBRM1 (0.44) SRD5A1PARP10PARP1CA1CA2
SCHEMBL30917717 0.81 CASP1 (0.44) HTTCA1CA2CA9ALDH1A1
SCHEMBL27527067 0.81 ACHE (0.47) ACHESRD5A1PARP10PARP1MAOB
SCHEMBL30917697 0.81 PBRM1 (0.44) SRD5A1PARP10PARP1CA1CA2
SCHEMBL30917551 0.81 CASP1 (0.44) HTTCA1CA2CA9ALDH1A1
SCHEMBL8617679 0.81 PBRM1 (0.44) SRD5A1PARP10PARP1CA1CA2
SCHEMBL31650648 0.81 PBRM1 (0.44) SRD5A1PARP10PARP1CA1CA2
SCHEMBL27560253 0.81 VHL (0.44) SRD5A1PARP10PARP1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105198722-B Method for asymmetrically catalyzing and synthesizing (R)-4, 7-dimethyl-1-tetralone 中国农业大学 2017-03-22 CN disclosed
CN-105198722-B Method for asymmetrically catalyzing and synthesizing (R)-4, 7-dimethyl-1-tetralone 中国农业大学 2017-03-22 CN disclosed
CN-105198722-A Method for asymmetrically catalyzing and synthesizing (R)-4, 7-dimethyl-1-tetralone UNIV CHINA AGRICULTURAL 2015-12-30 CN disclosed
CN-105198722-A Method for asymmetrically catalyzing and synthesizing (R)-4, 7-dimethyl-1-tetralone UNIV CHINA AGRICULTURAL 2015-12-30 CN disclosed