SCHEMBL861771

SCHEMBL861771

C=CCN1CCN(CC=CO)CC1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.37
RAB9A P51151 2/20 0.37
OPRD1 P41143 4/20 0.35
MAPT P10636 3/20 0.33
ADRA2A P08913 2/20 0.33
ADRA2B P18089 2/20 0.33
ADRA2C P18825 2/20 0.33
HRH3 Q9Y5N1 2/20 0.33
ADRA1A P35348 2/20 0.33
LMNA P02545 1/20 0.33
DRD2 P14416 1/20 0.33
HTR2A P28223 1/20 0.33
HRH1 P35367 1/20 0.33
DRD3 P35462 1/20 0.33
OPRK1 P41145 1/20 0.33
KDM4E B2RXH2 2/20 0.33
ALDH1A1 P00352 2/20 0.33
RAD52 P43351 1/20 0.33
ADRA1D P25100 1/20 0.32
ADRA1B P35368 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL861983 0.91 NPC1 (0.32) NPC1RAB9AOPRD1ADRA1AADRA1D
SCHEMBL7680464 0.89
SCHEMBL1072392 0.89 MEN1 (0.30) LMNA
SCHEMBL290880 0.84
SCHEMBL327601 0.84 OPRD1 (0.41) NPC1RAB9AOPRD1MAPTADRA2A
SCHEMBL6692977 0.84 OPRD1 (0.41) NPC1RAB9AOPRD1MAPTADRA2A
SCHEMBL3970107 0.84 OPRD1 (0.41) NPC1RAB9AOPRD1MAPTADRA2A
SCHEMBL861135 0.82
Bromide SCHEMBL7969410 0.81 OPRD1 (0.40) NPC1RAB9AOPRD1MAPTADRA2A
SCHEMBL9308707 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1709142-B1 DETERGENT / ANTI-OXIDANT ADDITIVES FOR FUELS AND LUBRICANTS CHEMTURA CORP (US) 2012-12-26 EP claimed
JP-4628371-B2 2011-02-09 JP claimed
US-7629300-B2 Detergent / anti-oxidant additives for lubricants CHEMTURA CORPORATION (US) 2009-12-08 US claimed
US-7621971-B2 Detergent/anti-oxidant additives for fuels CHEMTURA CORPORATION (US) 2009-11-24 US claimed
US-7618467-B2 Detergent / anti-oxidant additives for fuels and lubricants CHEMTURA CORPORATION (US) 2009-11-17 US claimed
US-20090088350-A1 DETERGENT / ANTI-OXIDANT ADDITIVES FOR LUBRICANTS LANXESS CANADA CO./CIE 2009-04-02 US claimed
US-20090084027-A1 DETERGENT / ANTI-OXIDANT ADDITIVES FOR FUELS LANXESS CANADA CO./CIE 2009-04-02 US claimed
JP-2007519812-A 2007-07-19 JP claimed
EP-1709142-A1 DETERGENT / ANTI-OXIDANT ADDITIVES FOR FUELS AND LUBRICANTS CHEMTURA CORPORATION (US) 2006-10-11 EP claimed
US-20050172543-A1 Detergent / anti-oxidant additives for fuels and lubricants LANXESS CANADA CO./CIE 2005-08-11 US claimed
WO-2005073352-A1 DETERGENT / ANTI-OXIDANT ADDITIVES FOR FUELS AND LUBRICANTS CHEMTURA CORPORATION (US) 2005-08-11 WO claimed
US-7629300-B2 Detergent / anti-oxidant additives for lubricants CHEMTURA CORPORATION (US) 2009-12-08 US disclosed
US-7621971-B2 Detergent/anti-oxidant additives for fuels CHEMTURA CORPORATION (US) 2009-11-24 US disclosed
US-7618467-B2 Detergent / anti-oxidant additives for fuels and lubricants CHEMTURA CORPORATION (US) 2009-11-17 US disclosed
US-20090084027-A1 DETERGENT / ANTI-OXIDANT ADDITIVES FOR FUELS LANXESS CANADA CO./CIE 2009-04-02 US disclosed
US-20090088350-A1 DETERGENT / ANTI-OXIDANT ADDITIVES FOR LUBRICANTS LANXESS CANADA CO./CIE 2009-04-02 US disclosed
EP-1709142-A1 DETERGENT / ANTI-OXIDANT ADDITIVES FOR FUELS AND LUBRICANTS CHEMTURA CORPORATION (US) 2006-10-11 EP disclosed
US-20050172543-A1 Detergent / anti-oxidant additives for fuels and lubricants LANXESS CANADA CO./CIE 2005-08-11 US disclosed
WO-2005073352-A1 DETERGENT / ANTI-OXIDANT ADDITIVES FOR FUELS AND LUBRICANTS CHEMTURA CORPORATION (US) 2005-08-11 WO disclosed