SCHEMBL861983

SCHEMBL861983

C=CCN1CCN(CC=CO)C1

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.32
RAB9A P51151 2/20 0.32
ADRA1D P25100 1/20 0.31
ADRA1A P35348 1/20 0.31
ADRA1B P35368 1/20 0.31
OPRD1 P41143 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL861135 0.91
SCHEMBL861771 0.91 NPC1 (0.37) NPC1RAB9AADRA1DADRA1AADRA1B
SCHEMBL4410856 0.85 ADRA1A (0.37) NPC1RAB9AADRA1DADRA1AADRA1B
SCHEMBL7680464 0.80
SCHEMBL1072392 0.80 MEN1 (0.30)
SCHEMBL6958212 0.76 OPRD1 (0.35) NPC1RAB9AADRA1DADRA1AADRA1B
SCHEMBL10406225 0.76 KDM4E (0.39) NPC1RAB9A
SCHEMBL2314084 0.75 ADRA1A (0.34) ADRA1DADRA1AADRA1BOPRD1
SCHEMBL15779877 0.74 RAB9A (0.32) NPC1RAB9AADRA1DADRA1AADRA1B
SCHEMBL290880 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1709142-B1 DETERGENT / ANTI-OXIDANT ADDITIVES FOR FUELS AND LUBRICANTS CHEMTURA CORP (US) 2012-12-26 EP claimed
JP-4628371-B2 2011-02-09 JP claimed
US-7629300-B2 Detergent / anti-oxidant additives for lubricants CHEMTURA CORPORATION (US) 2009-12-08 US claimed
US-7621971-B2 Detergent/anti-oxidant additives for fuels CHEMTURA CORPORATION (US) 2009-11-24 US claimed
US-7618467-B2 Detergent / anti-oxidant additives for fuels and lubricants CHEMTURA CORPORATION (US) 2009-11-17 US claimed
US-20090084027-A1 DETERGENT / ANTI-OXIDANT ADDITIVES FOR FUELS LANXESS CANADA CO./CIE 2009-04-02 US claimed
US-20090088350-A1 DETERGENT / ANTI-OXIDANT ADDITIVES FOR LUBRICANTS LANXESS CANADA CO./CIE 2009-04-02 US claimed
JP-2007519812-A 2007-07-19 JP claimed
EP-1709142-A1 DETERGENT / ANTI-OXIDANT ADDITIVES FOR FUELS AND LUBRICANTS CHEMTURA CORPORATION (US) 2006-10-11 EP claimed
US-20050172543-A1 Detergent / anti-oxidant additives for fuels and lubricants LANXESS CANADA CO./CIE 2005-08-11 US claimed
WO-2005073352-A1 DETERGENT / ANTI-OXIDANT ADDITIVES FOR FUELS AND LUBRICANTS CHEMTURA CORPORATION (US) 2005-08-11 WO claimed
EP-1709142-B1 DETERGENT / ANTI-OXIDANT ADDITIVES FOR FUELS AND LUBRICANTS CHEMTURA CORP (US) 2012-12-26 EP disclosed
US-7629300-B2 Detergent / anti-oxidant additives for lubricants CHEMTURA CORPORATION (US) 2009-12-08 US disclosed
US-7621971-B2 Detergent/anti-oxidant additives for fuels CHEMTURA CORPORATION (US) 2009-11-24 US disclosed
US-7618467-B2 Detergent / anti-oxidant additives for fuels and lubricants CHEMTURA CORPORATION (US) 2009-11-17 US disclosed
US-20090084027-A1 DETERGENT / ANTI-OXIDANT ADDITIVES FOR FUELS LANXESS CANADA CO./CIE 2009-04-02 US disclosed
US-20090088350-A1 DETERGENT / ANTI-OXIDANT ADDITIVES FOR LUBRICANTS LANXESS CANADA CO./CIE 2009-04-02 US disclosed
EP-1709142-A1 DETERGENT / ANTI-OXIDANT ADDITIVES FOR FUELS AND LUBRICANTS CHEMTURA CORPORATION (US) 2006-10-11 EP disclosed
US-20050172543-A1 Detergent / anti-oxidant additives for fuels and lubricants LANXESS CANADA CO./CIE 2005-08-11 US disclosed
WO-2005073352-A1 DETERGENT / ANTI-OXIDANT ADDITIVES FOR FUELS AND LUBRICANTS CHEMTURA CORPORATION (US) 2005-08-11 WO disclosed