Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | CD44 | P16070 | 1/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TYR | P14679 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9074167 | 0.81 | SMN1; SMN2 (0.42) | SMN1; SMN2CYP2C9CYP2C19TP53HIF1A | |
| SCHEMBL19198900 | 0.81 | SMN1; SMN2 (0.42) | SMN1; SMN2CYP2C9CYP2C19TP53HIF1A | |
| SCHEMBL30843769 | 0.81 | SMN1; SMN2 (0.42) | SMN1; SMN2CYP2C9CYP2C19TP53HIF1A | |
| SCHEMBL395983 | 0.80 | CYP2C9 (0.39) | SMN1; SMN2CYP2C9CYP2C19TP53HIF1A | |
| SCHEMBL7640687 | 0.78 | CYP1A2 (0.38) | SMN1; SMN2CYP2C9CYP2C19TP53HIF1A | |
| SCHEMBL10279383 | 0.76 | CD44 (0.42) | SMN1; SMN2CYP2C9CYP2C19TP53HIF1A | |
| SCHEMBL13145524 | 0.76 | CD44 (0.42) | SMN1; SMN2CYP2C9CYP2C19TP53HIF1A | |
| SCHEMBL29587642 | 0.76 | ALDH1A1 (0.58) | SMN1; SMN2CYP2C9CYP2C19TP53HIF1A | |
| SCHEMBL225785 | 0.76 | ALDH1A1 (0.58) | SMN1; SMN2CYP2C9CYP2C19TP53HIF1A | |
| SCHEMBL19203603 | 0.76 | SMN1; SMN2 (0.39) | SMN1; SMN2CYP2C9CYP2C19TP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776656-A | MULTILAYER WITH DIFFERENT OPTICAL CONSTANTS, CYANINE DYES, COMPLEX INDEX OF REFRACTION | TDK CORPORATION (JP) | 1998-07-07 | — | — | US | disclosed |