SCHEMBL8618032

SCHEMBL8618032

CC1=C(C)C2(CC1)C(=O)OC2=O

nearest known ligand 0.30

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 3/20 0.30
CYP3A4 P08684 3/20 0.30
MAPK1 P28482 3/20 0.30
HIF1A Q16665 2/20 0.30
LMNA P02545 2/20 0.30
CYP1A2 P05177 2/20 0.30
SMN1; SMN2 Q16637 2/20 0.30
NPC1 O15118 2/20 0.30
RAB9A P51151 2/20 0.30
NFKB1 P19838 1/20 0.30
THPO P40225 1/20 0.30
PPM1B O75688 1/20 0.30
PTPN1 P18031 1/20 0.30
PPP1CC P36873 1/20 0.30
TFPI2 P48307 1/20 0.30
PPP5C P53041 1/20 0.30
PPP2CA P67775 1/20 0.30
PPP1CA P62136 1/20 0.30
KDM4E B2RXH2 1/20 0.30
GMNN O75496 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8621453 0.87 GAA (0.31) TSHR
SCHEMBL22109759 0.69 TSHR (0.43) TP53LMNATSHR
SCHEMBL10904617 0.67
SCHEMBL8620336 0.63
SCHEMBL8841260 0.63 TP53 (0.35) TP53CYP3A4MAPK1HIF1ALMNA
SCHEMBL8619669 0.62
SCHEMBL21523570 0.61
SCHEMBL6675990 0.60 LMNA (0.31) CYP3A4LMNATSHR
SCHEMBL6999502 0.59 TP53 (0.32) TP53CYP3A4MAPK1HIF1ALMNA
SCHEMBL11164592 0.59 TP53 (0.32) TP53CYP3A4MAPK1HIF1ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0608132-B1 Coating varnish composition and antifouling coating composition HITACHI CHEMICAL CO LTD (JP) 1998-05-20 EP disclosed
US-5646198-A MIXTURE INCLUDES POLYMER, BENZOTRIAZOLE OR TRIAZOLE COMPOUND, AND COMPOUND WITH HYDROPHOBIC AND HYDROPHILIC PARTS; STORAGE STABILITY; MARINE STRUCTURES HITACHI CHEMICAL COMPANY, LTD. (JP) 1997-07-08 US disclosed
US-5439511-A Composition containing polymer obtained by polymerizing unsaturated acid anhydride and another unsaturated compound, specified additive HITACHI CHEMICAL COMPANY, LTD. (JP) 1995-08-08 US disclosed
EP-0659848-A2 Coating composition and antifouling paint Hitachi Chemical Co., Ltd. (JP) 1995-06-28 EP disclosed
EP-0608132-A1 Coating varnish composition and antifouling coating composition HITACHI CHEMICAL CO., LTD. (JP) 1994-07-27 EP disclosed