Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | P4HB | P07237 | 1/20 | 0.51 |
| ▸ | TACR3 | P29371 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8617544 | 0.89 | MEN1 (0.60) | RXFP1CYP3A4LMNAALDH1A1KMT2A | |
| SCHEMBL8617743 | 0.88 | CYP3A4 (0.65) | CYP3A4LMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL8615933 | 0.87 | CYP3A4 (0.52) | CYP3A4LMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL8615206 | 0.87 | CYP3A4 (0.52) | CYP3A4LMNAALDH1A1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL8620745 | 0.87 | CYP3A4 (0.64) | CYP3A4LMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL8617733 | 0.86 | CYP3A4 (0.58) | CYP3A4LMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL8619386 | 0.86 | LMNA (0.52) | CYP3A4LMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL8616493 | 0.83 | TACR3 (0.71) | CYP3A4LMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL8614931 | 0.82 | MAPT (0.56) | CYP3A4LMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL8612671 | 0.82 | KMT2A (0.65) | RXFP1CYP3A4ALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0726254-B1 | Quinoline-4-carbonylguanidine derivates, process for producing the same and pharmaceutical preparations containing the compounds | MITSUI TOATSU CHEMICALS (JP) | 1998-05-06 | — | — | EP | disclosed |
| US-5627193-A | MEDICAL DIAGNOSIS, CARDIOVASCULAR DIAORDERS AND PROTECTION OF ORGANS FOR TRANSPLANTATION | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-05-06 | — | — | US | disclosed |
| EP-0726254-A1 | Quinoline-4-carbonylguanidine derivates, process for producing the same and pharmaceutical preparations containing the compounds | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-08-14 | — | — | EP | disclosed |