Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.43 |
| ▸ | CDK4 | P11802 | 1/20 | 0.40 |
| ▸ | CCND1 | P24385 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.38 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8617222 | 0.90 | CDK4 (0.44) | CDK4CCND1MAOBMAPTALDH1A1 | |
| SCHEMBL8622477 | 0.89 | L3MBTL1 (0.46) | PTPN1CDK4CCND1HTR1AADRA1D | |
| SCHEMBL8623908 | 0.84 | HIF1A (0.46) | PTPN1MAOBHIF1AMEN1KMT2A | |
| SCHEMBL8620420 | 0.84 | HIF1A (0.44) | HTR1AADRA1DADRA1AADRA1BHIF1A | |
| SCHEMBL8622457 | 0.84 | L3MBTL1 (0.40) | CDK4CCND1HIF1AMAPTMEN1 | |
| SCHEMBL8621428 | 0.83 | MAPT (0.45) | MAOBHIF1AMAPTMEN1ALDH1A1 | |
| SCHEMBL8621226 | 0.82 | L3MBTL1 (0.46) | MAOBHIF1AMAPTALDH1A1POLB | |
| SCHEMBL8621319 | 0.82 | HIF1A (0.48) | MAOBHIF1AMAPTALDH1A1KMT2A | |
| SCHEMBL8620478 | 0.82 | MRGPRX4 (0.43) | CDK4CCND1HIF1AMAPTSMN1; SMN2 | |
| SCHEMBL8617286 | 0.82 | PTGDR2 (0.46) | CDK4CCND1MAPTMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0658541-B1 | PROCESS FOR PRODUCING CARBOXYLIC ACID DERIVATIVE | SHIONOGI & CO (JP) | 1998-05-20 | — | — | EP | disclosed |
| US-5510506-A | Process for producing carboxylic acid derivatives | SHIONOGI & CO., LTD. (JP) | 1996-04-23 | — | — | US | disclosed |
| EP-0658541-A1 | PROCESS FOR PRODUCING CARBOXYLIC ACID DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1995-06-21 | — | — | EP | disclosed |