Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8623908 | 0.91 | HIF1A (0.46) | MAOBMEN1KMT2AFFAR1HIF1A | |
| SCHEMBL8620428 | 0.89 | HIF1A (0.42) | MAPTHTTMAOBMEN1KMT2A | |
| SCHEMBL8621226 | 0.87 | L3MBTL1 (0.46) | MAPTMAOBNPC1HIF1APARP14 | |
| SCHEMBL8621319 | 0.87 | HIF1A (0.48) | MAPTHTTMAOBKMT2AHIF1A | |
| SCHEMBL8617222 | 0.85 | CDK4 (0.44) | MAPTMAOBKMT2AFFAR4L3MBTL1 | |
| SCHEMBL8617286 | 0.85 | PTGDR2 (0.46) | MAPTHTTNPC1MEN1KMT2A | |
| SCHEMBL8620478 | 0.85 | MRGPRX4 (0.43) | MAPTNPC1FFAR1FFAR4HIF1A | |
| SCHEMBL8617305 | 0.84 | ALDH1A1 (0.52) | MAPTMAOBNPC1MEN1KMT2A | |
| SCHEMBL8619246 | 0.84 | HIF1A (0.39) | MAOBHIF1AMAOA | |
| SCHEMBL8622457 | 0.84 | L3MBTL1 (0.40) | MAPTMEN1KMT2AHIF1AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0658541-B1 | PROCESS FOR PRODUCING CARBOXYLIC ACID DERIVATIVE | SHIONOGI & CO (JP) | 1998-05-20 | — | — | EP | disclosed |
| US-5510506-A | Process for producing carboxylic acid derivatives | SHIONOGI & CO., LTD. (JP) | 1996-04-23 | — | — | US | disclosed |
| EP-0658541-A1 | PROCESS FOR PRODUCING CARBOXYLIC ACID DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1995-06-21 | — | — | EP | disclosed |