Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 8/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8618371 | 1.00 | HIF1A (0.50) | HIF1ATP53HTTL3MBTL1ALDH1A1 | |
| SCHEMBL8619363 | 0.91 | HIF1A (0.47) | HIF1ATP53HTTALDH1A1MRGPRX4 | |
| SCHEMBL8619361 | 0.91 | HIF1A (0.47) | HIF1ATP53HTTALDH1A1MRGPRX4 | |
| SCHEMBL8618566 | 0.90 | HIF1A (0.56) | HIF1ATP53HTTNPSR1HPGD | |
| SCHEMBL8618563 | 0.90 | HIF1A (0.56) | HIF1ATP53HTTNPSR1HPGD | |
| SCHEMBL7664003 | 0.89 | HIF1A (0.49) | HIF1ATP53HTTALDH1A1MAPT | |
| SCHEMBL7664008 | 0.89 | HIF1A (0.49) | HIF1ATP53HTTALDH1A1MAPT | |
| SCHEMBL8622454 | 0.88 | HIF1A (0.52) | HIF1ATP53HTTL3MBTL1ALDH1A1 | |
| SCHEMBL8622450 | 0.88 | HIF1A (0.52) | HIF1ATP53HTTL3MBTL1ALDH1A1 | |
| SCHEMBL8396069 | 0.88 | HIF1A (0.51) | HIF1ATP53HTTL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0658541-B1 | PROCESS FOR PRODUCING CARBOXYLIC ACID DERIVATIVE | SHIONOGI & CO (JP) | 1998-05-20 | — | — | EP | disclosed |
| US-5510506-A | Process for producing carboxylic acid derivatives | SHIONOGI & CO., LTD. (JP) | 1996-04-23 | — | — | US | disclosed |
| EP-0658541-A1 | PROCESS FOR PRODUCING CARBOXYLIC ACID DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1995-06-21 | — | — | EP | disclosed |