Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL28291888 | 0.89 | LMNA (0.57) | ADRA2ALMNAL3MBTL1NPC1CYP1A2 | |
| SCHEMBL11763137 | 0.88 | ADRA2A (0.50) | ADRA2ALMNAADRA2BADRA2CL3MBTL1 | |
| SCHEMBL15173206 | 0.87 | ADRA2A (0.56) | ADRA2ALMNAADRA2BADRA2CL3MBTL1 | |
| Malonic Acid SCHEMBL8978416 | 0.87 | LMNA (0.55) | ADRA2ALMNAL3MBTL1NPC1CYP1A2 | |
| Bicarbonate SCHEMBL28218650 | 0.87 | LMNA (0.55) | ADRA2ALMNAL3MBTL1NPC1CYP1A2 | |
| Acetic Acid SCHEMBL28914683 | 0.87 | LMNA (0.55) | ADRA2ALMNAL3MBTL1NPC1CYP1A2 | |
| Methyl Alcohol SCHEMBL5316416 | 0.86 | LMNA (0.57) | ADRA2ALMNAADRA2BADRA2CL3MBTL1 | |
| Methylamine SCHEMBL28029473 | 0.86 | LMNA (0.57) | ADRA2ALMNAADRA2BADRA2CL3MBTL1 | |
| SCHEMBL4916223 | 0.86 | LMNA (0.61) | ADRA2ALMNAADRA2BADRA2CL3MBTL1 | |
| SCHEMBL7709 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5786428-A | POLYMER MATRIX OF UNSATURATED MONOMER AND METAL COMPLEX HAVING A LIGAND AND A POLYMERIZABLE UNSATURATED MOIETY; EFFICIENT, RAPID AND SIMPLE PURIFICATION; MEDICAL DIAGNOSIS; | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1998-07-28 | — | — | US | claimed |
| US-5786428-A | POLYMER MATRIX OF UNSATURATED MONOMER AND METAL COMPLEX HAVING A LIGAND AND A POLYMERIZABLE UNSATURATED MOIETY; EFFICIENT, RAPID AND SIMPLE PURIFICATION; MEDICAL DIAGNOSIS; | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1998-07-28 | — | — | US | disclosed |