Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 2/20 | 0.48 |
| ▸ | ACP1 | P24666 | 9/20 | 0.45 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8617940 | 0.88 | PLA2G2A (0.48) | ACP1CACNA2D1PDE10A | |
| SCHEMBL8616553 | 0.86 | ACP1 (0.42) | ACP1CACNA2D1 | |
| SCHEMBL8615126 | 0.85 | DHODH (0.47) | DHODHACP1CACNA2D1PDE10A | |
| SCHEMBL8619736 | 0.85 | DHODH (0.47) | DHODHACP1CACNA2D1PDE10A | |
| SCHEMBL8617753 | 0.83 | ACP1 (0.51) | ACP1PDE10A | |
| SCHEMBL8615447 | 0.83 | CACNA2D1 (0.38) | ACP1CACNA2D1 | |
| SCHEMBL8614839 | 0.83 | TACR3 (0.45) | DHODHACP1CACNA2D1PDE10A | |
| SCHEMBL8615355 | 0.82 | PDE10A (0.55) | ACP1PDE10A | |
| SCHEMBL8619039 | 0.82 | DHODH (0.46) | DHODHACP1CACNA2D1 | |
| SCHEMBL8620932 | 0.81 | POLB (0.51) | DHODHACP1PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0726254-B1 | Quinoline-4-carbonylguanidine derivates, process for producing the same and pharmaceutical preparations containing the compounds | MITSUI TOATSU CHEMICALS (JP) | 1998-05-06 | — | — | EP | disclosed |
| US-5627193-A | MEDICAL DIAGNOSIS, CARDIOVASCULAR DIAORDERS AND PROTECTION OF ORGANS FOR TRANSPLANTATION | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-05-06 | — | — | US | disclosed |
| EP-0726254-A1 | Quinoline-4-carbonylguanidine derivates, process for producing the same and pharmaceutical preparations containing the compounds | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-08-14 | — | — | EP | disclosed |