Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MOK | Q9UQ07 | 3/20 | 0.39 |
| ▸ | ACP1 | P24666 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | NQO2 | P16083 | 1/20 | 0.36 |
| ▸ | TACR3 | P29371 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8617931 | 0.92 | ACP1 (0.39) | MOKACP1MCHR1ABCB1ABCC1 | |
| SCHEMBL8615219 | 0.89 | ABCG2 (0.42) | MOKACP1ABCB1ABCC1ABCG2 | |
| SCHEMBL8613674 | 0.88 | TRPV1 (0.43) | MOKACP1MCHR1ABCB1ABCC1 | |
| SCHEMBL8616641 | 0.82 | ACP1 (0.42) | MOKACP1ABCB1ABCC1ABCG2 | |
| SCHEMBL8619423 | 0.82 | ADORA1 (0.50) | MOKACP1MCHR1ABCB1ABCC1 | |
| SCHEMBL8619222 | 0.80 | DHODH (0.45) | MOKACP1ADORA1NQO2TACR3 | |
| SCHEMBL8613853 | 0.80 | ALDH1A1 (0.52) | ACP1ABCB1ABCC1ABCG2MEN1 | |
| SCHEMBL8614838 | 0.80 | MEN1 (0.40) | ACP1ABCB1ABCC1ABCG2NQO2 | |
| SCHEMBL8615808 | 0.80 | KDM4E (0.50) | MOKACP1ABCB1ABCC1ABCG2 | |
| SCHEMBL8617766 | 0.80 | ABCB1 (0.54) | MOKABCB1ABCC1ABCG2ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0726254-B1 | Quinoline-4-carbonylguanidine derivates, process for producing the same and pharmaceutical preparations containing the compounds | MITSUI TOATSU CHEMICALS (JP) | 1998-05-06 | — | — | EP | disclosed |
| US-5627193-A | MEDICAL DIAGNOSIS, CARDIOVASCULAR DIAORDERS AND PROTECTION OF ORGANS FOR TRANSPLANTATION | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-05-06 | — | — | US | disclosed |
| EP-0726254-A1 | Quinoline-4-carbonylguanidine derivates, process for producing the same and pharmaceutical preparations containing the compounds | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-08-14 | — | — | EP | disclosed |