SCHEMBL8619124

SCHEMBL8619124

CCC/C=C/c1ccc(C#Cc2ccc(CCC)cc2)c(F)c1

nearest known ligand 0.39

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 11/20 0.39
FFAR4 Q5NUL3 2/20 0.39
ACACB O00763 4/20 0.35
TNNC1 P63316 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8619128 1.00 FFAR1 (0.39) FFAR1FFAR4ACACBTNNC1
SCHEMBL8616758 0.93 FFAR1 (0.44) FFAR1FFAR4ACACBTNNC1
SCHEMBL8616763 0.93 FFAR1 (0.44) FFAR1FFAR4ACACBTNNC1
SCHEMBL8618581 0.88 GRM5 (0.35) FFAR1FFAR4ACACB
SCHEMBL8618584 0.88 GRM5 (0.35) FFAR1FFAR4ACACB
SCHEMBL8618031 0.86 HAO1 (0.38) FFAR1FFAR4ACACB
SCHEMBL8618028 0.86 HAO1 (0.38) FFAR1FFAR4ACACB
SCHEMBL8621573 0.85 NFE2L2 (0.39) FFAR1FFAR4ACACB
SCHEMBL8621577 0.85 NFE2L2 (0.39) FFAR1FFAR4ACACB
SCHEMBL8623639 0.84 TNNC1 (0.42) FFAR1FFAR4ACACBTNNC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0648723-B1 Diphenylacetylene compound, process for preparing the same and liquid crystal composition and element comprising the same SUMITOMO CHEMICAL CO (JP) 1998-05-20 EP disclosed
US-5658489-A EXCELLENT ANISOTROPY OF REFRACTIVE INDEX; LOW VISCOSITY SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-08-19 US disclosed
EP-0648723-A1 Diphenylacetylene compound, process for preparing the same and liquid crystal composition and element comprising the same SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1995-04-19 EP disclosed