SCHEMBL861952

SCHEMBL861952

CC(C)CCC(C)Nc1ccc(N(c2ccccc2)c2ccc(NC(C)CCC(C)C)cc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.47
CYP3A4 P08684 4/20 0.47
ALOX15 P16050 3/20 0.47
TSHR P16473 3/20 0.47
HSD17B10 Q99714 3/20 0.47
ALOX12 P18054 3/20 0.47
HIF1A Q16665 2/20 0.47
MAPK1 P28482 1/20 0.47
TDP1 Q9NUW8 4/20 0.46
L3MBTL1 Q9Y468 3/20 0.46
SMN1; SMN2 Q16637 3/20 0.46
THRB P10828 2/20 0.46
TP53 P04637 1/20 0.46
HSP90AA1 P07900 1/20 0.46
CASP1 P29466 1/20 0.46
MAPT P10636 3/20 0.38
HTT P42858 3/20 0.38
KDM4E B2RXH2 2/20 0.38
LMNA P02545 2/20 0.38
RECQL P46063 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1134060 0.93 ALDH1A1 (0.52) ALDH1A1CYP3A4ALOX15TSHRHSD17B10
SCHEMBL16963031 0.87 ALDH1A1 (0.45) ALDH1A1CYP3A4ALOX15TSHRHSD17B10
SCHEMBL8589385 0.85 ALDH1A1 (0.67) ALDH1A1CYP3A4ALOX15TSHRHSD17B10
SCHEMBL862039 0.85 ALDH1A1 (0.67) ALDH1A1CYP3A4ALOX15TSHRHSD17B10
SCHEMBL1899338 0.84 ALDH1A1 (0.58) ALDH1A1CYP3A4ALOX15TSHRHSD17B10
SCHEMBL27883347 0.83 ALDH1A1 (0.42) ALDH1A1CYP3A4ALOX15TSHRHSD17B10
SCHEMBL39071 0.82 ALDH1A1 (0.58) ALDH1A1CYP3A4ALOX15TSHRHSD17B10
SCHEMBL201628 0.81 ALDH1A1 (0.71) ALDH1A1CYP3A4ALOX15TSHRHSD17B10
SCHEMBL28306584 0.79 CACNA2D1 (0.36) ALDH1A1CYP3A4ALOX15TSHRHSD17B10
SCHEMBL853912 0.78 TDP1 (0.64) ALDH1A1CYP3A4ALOX15TSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8763660-B2 Tire belt incorporating an antioxidant agent MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) 2014-07-01 US claimed
US-20110203712-A1 Rubber Composition for Tires Incorporating a Novel Antioxidant System MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) 2011-08-25 US claimed
EP-2092010-B1 RUBBER COMPOSITION FOR TYRES INCORPORATING A NOVEL ANTIOXIDANT SYSTEM TECHNOLOGIE MICHELIN S A SOC D (FR) 2011-01-26 EP claimed
US-20100063189-A1 RUBBER COMPOSITION FOR TYRES INCORPORATING A NOVEL ANTIOXIDANT SYSTEM MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) 2010-03-11 US claimed
EP-2092010-A1 RUBBER COMPOSITION FOR TYRES INCORPORATING A NOVEL ANTIOXIDANT SYSTEM Societe de Technologie Michelin S.A. (FR) 2009-08-26 EP claimed
US-20090165919-A1 TYRE BELT INCORPORATING AN ANTIOXIDANT AGENT MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) 2009-07-02 US claimed
EP-2013038-A1 TYRE BELT INCORPORATING AN ANTI-OXIDANT AGENT Societe de Technologie Michelin (FR) 2009-01-14 EP claimed
WO-2008055683-A1 RUBBER COMPOSITION FOR TYRES INCORPORATING A NOVEL ANTIOXIDANT SYSTEM SOCIETE DE TECHNOLOGIE MICHELIN (FR) 2008-05-15 WO claimed
WO-2007121936-A1 TYRE BELT INCORPORATING AN ANTI-OXIDANT AGENT SOCIETE DE TECHNOLOGIE MICHELIN (FR) 2007-11-01 WO claimed
US-11987671-B2 Elastomer mix comprising PLLA and PDLA COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2024-05-21 US disclosed
EP-3555196-B1 METHOD FOR PRODUCING A DIENE ELASTOMER MODIFIED WITH A 1,3-DIPOLAR COMPOUND MICHELIN & CIE (FR) 2023-04-05 EP disclosed
US-11370866-B2 Method for producing a diene elastomer modified with a 1,3-dipolar compound COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2022-06-28 US disclosed
US-11155665-B2 Process for preparing polydiene/polylactide copolymers by reactive extrusion COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2021-10-26 US disclosed
US-20210253801-A1 ELASTOMER MIX COMPRISING PLLA AND PDLA COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2021-08-19 US disclosed
US-20090165919-A1 TYRE BELT INCORPORATING AN ANTIOXIDANT AGENT MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) 2009-07-02 US disclosed
US-20090165919-A1 TYRE BELT INCORPORATING AN ANTIOXIDANT AGENT MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) 2009-07-02 US disclosed
EP-2013038-A1 TYRE BELT INCORPORATING AN ANTI-OXIDANT AGENT Societe de Technologie Michelin (FR) 2009-01-14 EP disclosed
WO-2008055683-A1 RUBBER COMPOSITION FOR TYRES INCORPORATING A NOVEL ANTIOXIDANT SYSTEM SOCIETE DE TECHNOLOGIE MICHELIN (FR) 2008-05-15 WO disclosed
WO-2007121936-A1 TYRE BELT INCORPORATING AN ANTI-OXIDANT AGENT SOCIETE DE TECHNOLOGIE MICHELIN (FR) 2007-11-01 WO disclosed
WO-2007121936-A1 TYRE BELT INCORPORATING AN ANTI-OXIDANT AGENT SOCIETE DE TECHNOLOGIE MICHELIN (FR) 2007-11-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090165919-A1 TYRE BELT INCORPORATING AN ANTIOXIDANT AGENT POT1, GPX4, GPX1 ALDH1A1 999/4885CYP3A4 1331/4885ALOX15 478/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.