Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 7/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL465078 | 0.81 | LTA4H (0.44) | KCNH2SMN1; SMN2LMNADRD2DRD3 | |
| SCHEMBL10537771 | 0.78 | ALDH1A1 (0.47) | SMN1; SMN2HSD17B10LMNAALDH1A1CYP3A4 | |
| SCHEMBL5548770 | 0.76 | MGLL (0.48) | SMN1; SMN2NPC1RAB9AHSD17B10LMNA | |
| SCHEMBL2696251 | 0.75 | LTA4H (0.43) | KCNH2SMN1; SMN2LMNADRD2DRD3 | |
| SCHEMBL8619647 | 0.75 | LTA4H (0.39) | KCNH2SMN1; SMN2LMNAPPARADRD2 | |
| SCHEMBL10541387 | 0.75 | ALDH1A1 (0.47) | SMN1; SMN2HSD17B10LMNAALDH1A1CYP3A4 | |
| SCHEMBL3098844 | 0.73 | ELANE (0.50) | SMN1; SMN2RAB9ALMNAPPARAALDH1A1 | |
| SCHEMBL701779 | 0.73 | LTA4H (0.47) | KCNH2SMN1; SMN2LMNADRD2DRD3 | |
| SCHEMBL1722454 | 0.71 | NPC1 (0.42) | KCNH2SMN1; SMN2NPC1RAB9AHSD17B10 | |
| SCHEMBL8042127 | 0.71 | LTA4H (0.39) | KCNH2SMN1; SMN2LMNAPPARADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0890596-B1 | Process for the preparation of poly (arylcarbonate)s | GEN ELECTRIC (US) | 2007-12-05 | — | — | EP | claimed |