SCHEMBL349565

SCHEMBL349565

CCO/N=C(\C(=O)O)c1ccccc1COc1ccccc1C

nearest known ligand 0.62

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.47
TP53 P04637 1/20 0.47
RXRA P19793 1/20 0.44
RXRB P28702 1/20 0.44
RXRG P48443 1/20 0.44
PTGDR2 Q9Y5Y4 2/20 0.43
ALDH1A1 P00352 2/20 0.41
MRGPRX4 Q96LA9 2/20 0.41
RECQL P46063 1/20 0.41
TDP1 Q9NUW8 3/20 0.40
HIF1A Q16665 2/20 0.39
SGMS2 Q8NHU3 1/20 0.39
KDM4E B2RXH2 1/20 0.39
FOLH1 Q04609 1/20 0.39
FFAR1 O14842 1/20 0.39
FFAR4 Q5NUL3 1/20 0.39
MAPT P10636 1/20 0.39
NOTUM Q6P988 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL674085 1.00 HTT (0.47) HTTTP53RXRARXRBRXRG
SCHEMBL26650771 1.00 HTT (0.47) HTTTP53RXRARXRBRXRG
SCHEMBL8622758 0.89 TP53 (0.46) HTTTP53RXRARXRBRXRG
SCHEMBL8622760 0.89 TP53 (0.46) HTTTP53RXRARXRBRXRG
SCHEMBL8619689 0.89 PTGDR2 (0.45) HTTTP53PTGDR2ALDH1A1MRGPRX4
SCHEMBL8619691 0.89 PTGDR2 (0.45) HTTTP53PTGDR2ALDH1A1MRGPRX4
SCHEMBL6899784 0.88 HIF1A (0.51) HTTTP53RXRARXRBRXRG
SCHEMBL435569 0.88 HIF1A (0.51) HTTTP53RXRARXRBRXRG
SCHEMBL435570 0.88 HIF1A (0.51) HTTTP53RXRARXRBRXRG
SCHEMBL8624580 0.88 MRGPRX4 (0.53) HTTTP53PTGDR2MRGPRX4HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 134 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2595481-B1 CONTROL AGENT FOR SOFT ROT AND CONTROL METHOD FOR THE SAME ISHIHARA SANGYO KAISHA (JP) 2016-07-13 EP claimed
EP-0855859-B1 SYNERGISTIC FUNGICIDAL COMPOSITION INCLUDING A STROBILURIN ANALOGUE COMPOUND BAYER CROPSCIENCE SA (FR) 2003-03-12 EP claimed
EP-0979034-B1 COMPOSITION FOR CONTROLLING HARMFUL BIO-ORGANISMS AND METHOD FOR CONTROLLING HARMFUL BIO-ORGANISMS USING THE SAME ISHIHARA SANGYO KAISHA (JP) 2003-02-26 EP claimed
US-20030027720-A1 Synergistic fungicidal composition comprising a compound analogous to strobilurin DUVERT PATRICE (FR) 2003-02-06 US claimed
EP-0712278-B1 N-PYRIDYLTOLUIDINE-CONTAINING FUNGICIDAL WATER DISPERSIBLE GRANULES ISHIHARA SANGYO KAISHA (JP) 2001-06-13 EP claimed
JP-8225411-A None JP disclosed
EP-2181593-B2 Use of specific alcohol alkoxylates as adjuvant for the agrotechnical sector BASF SE (DE) 2022-02-23 EP disclosed
US-10759767-B2 Compositions comprising a triazole compound BASF Agro B.V. (NL) 2020-09-01 US disclosed
US-10206391-B2 Strobilurin formulations VIVE CROP PROTECTION INC. (CA) 2019-02-19 US disclosed
US-9474277-B2 Pyrazole compound and pesticidal mixtures comprising a pyrazole compound BASF SE (DE) 2016-10-25 US disclosed
EP-2181593-B1 Use of specific alcohol alkoxylates as adjuvant for the agrotechnical sector BASF SE (DE) 2016-08-24 EP disclosed
EP-2595481-B1 CONTROL AGENT FOR SOFT ROT AND CONTROL METHOD FOR THE SAME ISHIHARA SANGYO KAISHA (JP) 2016-07-13 EP disclosed
EP-0949243-A1 OPTICALLY ACTIVE METHOXYIMINOACETAMIDE DERIVATIVES, PROCESS FOR THE PREPARATION OF THEM, INTERMEDIATES THEREFOR, AND PESTICIDES CONTAINING THEM AS THE ACTIVE INGREDIENT MITSUBISHI CHEMICAL CORPORATION (JP) 1999-10-13 EP disclosed
EP-0934935-A1 Heterocyclic substituted phenyl compounds, process and intermediates for their preparation and their use as fungicides and pesticides BASF AKTIENGESELLSCHAFT (DE) 1999-08-11 EP disclosed
EP-0920248-A1 BIOLOGICAL MATERIAL EMBEDDED IN HYDROGELS, A PROCESS FOR THE EMBEDDING THEREOF, AND ITS USE AS ARTIFICIAL SEED BAYER AG (DE) 1999-06-09 EP disclosed
EP-0658541-B1 PROCESS FOR PRODUCING CARBOXYLIC ACID DERIVATIVE SHIONOGI & CO (JP) 1998-05-20 EP disclosed
WO-1998005197-A1 BIOLOGICAL MATERIAL EMBEDDED IN HYDROGELS, A PROCESS FOR THE EMBEDDING THEREOF, AND ITS USE AS ARTIFICIAL SEED BAYER AKTIENGESELLSCHAFT (DE) 1998-02-12 WO disclosed
JP-H08225411-A GERMICIDAL COMPOSITION FOR AGRICULTURE AND HORTICULTURE NIPPON SODA CO LTD 1996-09-03 JP disclosed
US-5510506-A Process for producing carboxylic acid derivatives SHIONOGI & CO., LTD. (JP) 1996-04-23 US disclosed
EP-0658541-A1 PROCESS FOR PRODUCING CARBOXYLIC ACID DERIVATIVE SHIONOGI & CO., LTD. (JP) 1995-06-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030027720-A1 Synergistic fungicidal composition comprising a compound analogous to strobilurin CYP51A1, PFN1, PIR HTT 2351/4885TP53 766/4885RXRA 2258/4885
US-10206391-B2 Strobilurin formulations CD63, SNU13, SNX1 HTT 3023/4885TP53 92/4885RXRA 4603/4885
US-10759767-B2 Compositions comprising a triazole compound CYP1B1, CYP3A5, CYP4B1 HTT 3238/4885TP53 3413/4885RXRA 2471/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.