Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.38 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.35 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.35 |
| ▸ | GRIK3 | Q13003 | 2/20 | 0.35 |
| ▸ | GRIK4 | Q16099 | 2/20 | 0.35 |
| ▸ | GRIK5 | Q16478 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | GRIA1 | P42261 | 3/20 | 0.33 |
| ▸ | GRIA2 | P42262 | 3/20 | 0.33 |
| ▸ | GRIA3 | P42263 | 3/20 | 0.33 |
| ▸ | GRIA4 | P48058 | 3/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8616755 | 0.93 | SIRT2 (0.37) | SIRT2GRIK1GRIK2GRIK3GRIK4 | |
| SCHEMBL8624320 | 0.90 | SIRT2 (0.35) | SIRT2GRIK1GRIK2GRIK3GRIK4 | |
| SCHEMBL8616748 | 0.89 | SIRT2 (0.39) | SIRT2GRIK1GRIK2GRIK3GRIK4 | |
| SCHEMBL8621415 | 0.88 | SIRT2 (0.38) | SIRT2GRIK1GRIK2GRIK3GRIK4 | |
| SCHEMBL8624831 | 0.87 | SIRT2 (0.40) | SIRT2GRIK1GRIK2GRIK3GRIK4 | |
| SCHEMBL8624317 | 0.85 | KDM4E (0.51) | GRIK1GRIK2GRIK3GRIK4GRIK5 | |
| SCHEMBL8616707 | 0.85 | SIRT2 (0.38) | SIRT2GRIK1GRIK2GRIK3GRIK4 | |
| SCHEMBL9036662 | 0.84 | SIRT2 (0.31) | SIRT2LMNAMAPT | |
| SCHEMBL8622359 | 0.82 | SIRT2 (0.39) | SIRT2GRIK1GRIK2GRIK3GRIK4 | |
| SCHEMBL8620799 | 0.79 | SIRT2 (0.37) | SIRT2GRIN2DGRIN3BLMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5710138-A | Benzo f!quinoxalinedione derivatives, their production and use in pharmaceutical agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-01-20 | — | — | US | disclosed |
| EP-0696289-B1 | BENZO[F]QUINOXALINDIONE DERIVATIVES, THEIR PREPARATION AND THEIR USE IN DRUGS | SCHERING AG (DE) | 1997-03-12 | — | — | EP | disclosed |
| WO-1994025470-A1 | BENZO[F]QUINOXALINDIONE DERIVATIVES, THEIR PREPARATION AND THEIR USE IN DRUGS | SCHERING AKTIENGESELLSCHAFT (DE) | 1994-11-10 | — | — | WO | disclosed |