Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8624320 | 0.93 | SIRT2 (0.35) | SIRT2ALDH1A1LMNAGAAMAPT | |
| SCHEMBL8616755 | 0.91 | SIRT2 (0.37) | SIRT2LMNAMAPT | |
| SCHEMBL8621415 | 0.90 | SIRT2 (0.38) | SIRT2 | |
| SCHEMBL8619987 | 0.84 | SIRT2 (0.38) | SIRT2LMNAMAPT | |
| SCHEMBL8620799 | 0.82 | SIRT2 (0.37) | SIRT2ALDH1A1LMNAGAAMAPT | |
| SCHEMBL9036978 | 0.80 | SIRT2 (0.32) | SIRT2 | |
| SCHEMBL8622359 | 0.79 | SIRT2 (0.39) | SIRT2LMNAMAPT | |
| SCHEMBL8616748 | 0.79 | SIRT2 (0.39) | SIRT2LMNAMAPT | |
| SCHEMBL8622998 | 0.78 | KDM4E (0.49) | ALDH1A1MAPT | |
| SCHEMBL8618985 | 0.77 | SIRT2 (0.37) | SIRT2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696289-A1 | BENZO F]QUINOXALINDIONE DERIVATIVES, THEIR PREPARATION AND THEIR USE IN DRUGS | SCHERING AG (DE) | 1996-02-14 | — | — | EP | disclosed |