Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGPL1 | O95470 | 11/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6556838 | 0.99 | SGPL1 (0.48) | SGPL1MEN1KMT2AKDM4EGAA | |
| SCHEMBL6555294 | 0.86 | MEN1 (0.61) | MEN1KMT2AL3MBTL1KDM1AMAOA | |
| SCHEMBL6556931 | 0.85 | MEN1 (0.60) | MEN1KMT2AL3MBTL1KDM1AMAOA | |
| SCHEMBL6556099 | 0.85 | MEN1 (0.60) | MEN1KMT2AL3MBTL1KDM1AMAOA | |
| SCHEMBL8620404 | 0.85 | CYP2D6 (0.50) | SGPL1MEN1KMT2AGAAL3MBTL1 | |
| Hydrochloric Acid SCHEMBL8620287 | 0.84 | MEN1 (0.59) | MEN1KMT2ATDP1L3MBTL1BCHE | |
| SCHEMBL6555183 | 0.84 | CYP2D6 (0.49) | SGPL1MEN1KMT2AKDM4EGAA | |
| SCHEMBL6555248 | 0.84 | MEN1 (0.61) | MEN1KMT2AL3MBTL1KDM1AMAOA | |
| SCHEMBL8621981 | 0.83 | TACR1 (0.48) | SGPL1MEN1KMT2AKDM4EGAA | |
| SCHEMBL8621287 | 0.82 | SGPL1 (0.52) | SGPL1MEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0613458-B1 | ACYCLIC ETHYLENEDIAMINE DERIVATIVES AS SUBSTANCE P RECEPTOR ANTAGONISTS | PFIZER (US) | 1998-01-07 | — | — | EP | disclosed |
| US-5521220-A | Acyclic ethylenediamine derivatives | PFIZER INC. (US) | 1996-05-28 | — | — | US | disclosed |
| WO-1993010073-A1 | ACYCLIC ETHYLENEDIAMINE DERIVATIVES AS SUBSTANCE P RECEPTOR ANTAGONISTS | PFIZER INC. (US) | 1993-05-27 | — | — | WO | disclosed |