Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGPL1 | O95470 | 14/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6557014 | 0.83 | MEN1 (0.73) | MEN1KMT2AKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL8620824 | 0.82 | MEN1 (0.71) | MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL8620048 | 0.82 | SGPL1 (0.49) | SGPL1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL8621274 | 0.82 | MEN1 (0.52) | SGPL1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL6556838 | 0.81 | SGPL1 (0.48) | SGPL1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL8626711 | 0.80 | MEN1 (0.50) | SGPL1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL6557248 | 0.70 | MEN1 (0.69) | MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL9229921 | 0.70 | MEN1 (0.69) | MEN1KMT2AKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL8621357 | 0.69 | MEN1 (0.68) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL8619143 | 0.69 | MEN1 (0.68) | MEN1KMT2AKDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0613458-B1 | ACYCLIC ETHYLENEDIAMINE DERIVATIVES AS SUBSTANCE P RECEPTOR ANTAGONISTS | PFIZER (US) | 1998-01-07 | — | — | EP | disclosed |
| US-5521220-A | Acyclic ethylenediamine derivatives | PFIZER INC. (US) | 1996-05-28 | — | — | US | disclosed |