Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.57 |
| ▸ | HPGD | P15428 | 7/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.48 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL866062 | 0.90 | ALDH1A1 (0.64) | ALDH1A1HPGDKDM4ETSHRHTT | |
| SCHEMBL3688021 | 0.88 | ALDH1A1 (0.62) | ALDH1A1HPGDKDM4ETSHRHTT | |
| SCHEMBL31267470 | 0.88 | ALDH1A1 (0.62) | ALDH1A1HPGDKDM4ETSHRHTT | |
| SCHEMBL31267447 | 0.86 | ALDH1A1 (0.68) | ALDH1A1HPGDKDM4ETSHRHTT | |
| SCHEMBL4922153 | 0.85 | HTT (0.62) | ALDH1A1HPGDKDM4ETSHRHTT | |
| SCHEMBL30827780 | 0.85 | HTT (0.62) | ALDH1A1HPGDKDM4ETSHRHTT | |
| SCHEMBL5674955 | 0.83 | TSHR (0.77) | ALDH1A1HPGDKDM4ETSHRHTT | |
| SCHEMBL8620126 | 0.83 | ALDH1A1 (0.57) | ALDH1A1HPGDKDM4ETSHRHTT | |
| SCHEMBL4914527 | 0.83 | ALDH1A1 (0.57) | ALDH1A1HPGDKDM4ETSHRHTT | |
| SCHEMBL8515238 | 0.83 | ALDH1A1 (0.57) | ALDH1A1HPGDKDM4ETSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5767121-A | ANTIINFLAMMATORY AND -ARTHRITIC AGENTS; ANTIPYRETICS; ANALGESICS; ADHESION PROTEIN EXPRESSION AND CYCLOXYGENASE AND 5-LIPOXYGENASE INHIBITORS; IMMUNOSUPPRESSANTS AND -MODULATORS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-06-16 | — | — | US | disclosed |