SCHEMBL866062

SCHEMBL866062

Nc1ccccc1C(=O)NCCCNC(=O)c1ccccc1N

nearest known ligand 0.71

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.64
HPGD P15428 7/20 0.64
KDM4E B2RXH2 6/20 0.64
TSHR P16473 1/20 0.59
HTT P42858 1/20 0.59
HSD17B10 Q99714 2/20 0.57
TP53 P04637 1/20 0.57
MAPK1 P28482 1/20 0.57
SMN1; SMN2 Q16637 1/20 0.57
LMNA P02545 1/20 0.55
RCE1 Q9Y256 1/20 0.53
HDAC3 O15379 4/20 0.52
HDAC1 Q13547 4/20 0.52
ALOX5 P09917 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31267470 0.94 ALDH1A1 (0.62) ALDH1A1HPGDKDM4ETSHRHTT
SCHEMBL3688021 0.94 ALDH1A1 (0.62) ALDH1A1HPGDKDM4ETSHRHTT
SCHEMBL31267447 0.92 ALDH1A1 (0.68) ALDH1A1HPGDKDM4ETSHRHTT
SCHEMBL4922153 0.91 HTT (0.62) ALDH1A1HPGDKDM4ETSHRHTT
SCHEMBL30827780 0.91 HTT (0.62) ALDH1A1HPGDKDM4ETSHRHTT
SCHEMBL5674955 0.90 TSHR (0.77) ALDH1A1HPGDKDM4ETSHRHTT
SCHEMBL8620126 0.90 ALDH1A1 (0.57) ALDH1A1HPGDKDM4ETSHRHTT
SCHEMBL4914527 0.90 ALDH1A1 (0.57) ALDH1A1HPGDKDM4ETSHRHTT
SCHEMBL8515238 0.90 ALDH1A1 (0.57) ALDH1A1HPGDKDM4ETSHRHTT
SCHEMBL8620123 0.90 ALDH1A1 (0.57) ALDH1A1HPGDKDM4ETSHRHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118027412-A Photo-alignment material 罗利克技术有限公司 2024-05-14 CN disclosed
WO-2023174773-A1 PHOTOALIGNING MATERIALS Rolic Technologies AG (CH) 2023-09-21 WO disclosed
US-11634544-B2 Photoaligning materials Rolic Technologies AG (CH) 2023-04-25 US disclosed
US-20210340330-A1 PHOTOALIGNING MATERIALS Rolic Technologies AG (CH) 2021-11-04 US disclosed
CN-108912011-B Photoalignment material 罗立克科技股份公司 2021-09-24 CN disclosed
CN-104649916-B Photocrosslinkable materials 罗利克有限公司 2020-12-01 CN disclosed
US-20200223984-A1 PHOTOALIGNING MATERIALS Rolic Technologies AG (CH) 2020-07-16 US disclosed
US-10696795-B2 Photoaligning materials Rolic Technologies AG (CH) 2020-06-30 US disclosed
EP-3374467-B1 COMPOSITIONS OF PHOTO-ALIGNABLE MATERIALS ROLIC TECH AG (CH) 2020-04-15 EP disclosed
CN-109804306-A Light orientation copolymer material 罗利克技术有限公司 2019-05-24 CN disclosed
US-20130004679-A1 PHOTOCROSSLINKABLE MATERIALS ROLIC AG (CH) 2013-01-03 US disclosed
US-8329823-B2 Photocrosslinkable materials ROLIC AG (CH) 2012-12-11 US disclosed
US-8173749-B2 Photocrosslinkable materials ROLIC AG (CH) 2012-05-08 US disclosed
US-20120076952-A1 PHOTOCROSSLINKABLE MATERIALS ROLIC AG (CH) 2012-03-29 US disclosed
EP-2308826-A1 Photocrosslinkable materials Rolic AG (CH) 2011-04-13 EP disclosed
EP-2308827-A1 Photocrosslinkable materials Rolic AG (CH) 2011-04-13 EP disclosed
EP-2305632-A1 Photocrosslinkable materials Rolic AG (CH) 2011-04-06 EP disclosed
EP-2305631-A1 Photocrosslinkable materials Rolic AG (CH) 2011-04-06 EP disclosed
US-20100048849-A1 PHOTOCROSSLINKABLE MATERIALS COMPRISING ALICYCLIC GROUP ROLIC AG (CH) 2010-02-25 US disclosed
US-20080293888-A1 Photocrosslinkable Materials ROLIC AG (CH) 2008-11-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100048849-A1 PHOTOCROSSLINKABLE MATERIALS COMPRISING ALICYCLIC GROUP DDC, ALAD, DYNC1LI1 ALDH1A1 97/4885HPGD 1068/4885KDM4E 1369/4885
US-20080293888-A1 Photocrosslinkable Materials DDC, PARG, ALAD ALDH1A1 313/4885HPGD 852/4885KDM4E 1831/4885
US-20120076952-A1 PHOTOCROSSLINKABLE MATERIALS DDC, PARG, ALAD ALDH1A1 313/4885HPGD 852/4885KDM4E 1831/4885
US-20130004679-A1 PHOTOCROSSLINKABLE MATERIALS DDC, PARG, ALAD ALDH1A1 313/4885HPGD 852/4885KDM4E 1831/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.