Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 15/20 | 0.48 |
| ▸ | CCKAR | P32238 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CDC25A | P30304 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8897693 | 0.86 | CCKBR (0.60) | CCKBRCCKARCDC25A | |
| SCHEMBL7041976 | 0.83 | CCKBR (0.50) | CCKBRCCKARCDC25A | |
| SCHEMBL8638401 | 0.82 | CCKBR (0.59) | CCKBRCCKAR | |
| SCHEMBL4424441 | 0.81 | GAA (0.46) | POLB | |
| SCHEMBL8547144 | 0.80 | CCKBR (0.60) | CCKBR | |
| SCHEMBL8543405 | 0.80 | CCKBR (0.60) | CCKBRCCKAR | |
| SCHEMBL5711037 | 0.79 | ALDH1A1 (0.44) | CCKBRCCKAR | |
| SCHEMBL8562037 | 0.78 | ALDH1A1 (0.47) | CCKBRCCKAR | |
| SCHEMBL8638391 | 0.78 | CCKBR (0.64) | CCKBR | |
| SCHEMBL8615099 | 0.75 | CCKBR (0.56) | CCKBRCCKAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0623118-B1 | CARBAMATE DERIVATIVES AND THEIR USE IN MEDICINE | GLAXO WELLCOME SPA (IT) | 1998-05-13 | — | — | EP | disclosed |
| US-5486514-A | GASTRIN, CHOLECYSTOKININ RECEPTOR ANTAGONISTS | GLAXO SPA (IT) | 1996-01-23 | — | — | US | disclosed |