Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 17/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12729604 | 1.00 | STING1 (0.46) | STING1POLBPDE3BPDE3A | |
| SCHEMBL17037317 | 0.86 | STING1 (0.49) | STING1 | |
| SCHEMBL21049964 | 0.86 | STING1 (0.49) | STING1 | |
| SCHEMBL22984000 | 0.85 | KDM4E (0.40) | STING1 | |
| SCHEMBL25504661 | 0.85 | KDM4E (0.40) | STING1 | |
| SCHEMBL23326714 | 0.84 | STING1 (0.41) | STING1PDE3BPDE3A | |
| SCHEMBL8668421 | 0.83 | NT5E (0.36) | STING1PDE3A | |
| SCHEMBL14946363 | 0.82 | STING1 (0.60) | STING1PDE3BPDE3A | |
| SCHEMBL22983981 | 0.82 | STING1 (0.60) | STING1PDE3BPDE3A | |
| SCHEMBL9964274 | 0.82 | STING1 (0.60) | STING1PDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756704-A | Nucleosides and nucleoside derivatives containing enzymatically cleavable protecting groups | BOEHRINGER MANNHEIM GMBH (DE) | 1998-05-26 | — | — | US | disclosed |
| US-5677441-A | Nucleosides, nucleotides and oligonucleotides containing enzymatically cleavable protecting groups | BOEHRINGER MANNHEIM GMBH (DE) | 1997-10-14 | — | — | US | disclosed |
| EP-0649855-A1 | Use of nucleosides and nucleoside derivatives with enzymatically cleavable protecting groupes in the synthesis of oligonucleotiden | Roche Diagnostics GmbH (DE) | 1995-04-26 | — | — | EP | disclosed |