Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | POLA1 | P09884 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.34 |
| ▸ | STING1 | Q86WV6 | 12/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25504661 | 1.00 | KDM4E (0.40) | KDM4EPOLA1TAS1R3TAS1R1STING1 | |
| SCHEMBL8620596 | 0.85 | STING1 (0.46) | STING1 | |
| SCHEMBL12729604 | 0.85 | STING1 (0.46) | STING1 | |
| SCHEMBL25504663 | 0.84 | STING1 (0.44) | TAS1R3TAS1R1STING1ALDH1A1 | |
| SCHEMBL22984011 | 0.84 | STING1 (0.44) | TAS1R3TAS1R1STING1ALDH1A1 | |
| SCHEMBL12621476 | 0.84 | STING1 (0.44) | TAS1R3TAS1R1STING1ALDH1A1 | |
| SCHEMBL19491649 | 0.84 | STING1 (0.44) | TAS1R3TAS1R1STING1ALDH1A1 | |
| SCHEMBL6896069 | 0.83 | KDM4E (0.36) | KDM4EPOLA1TAS1R3TAS1R1STING1 | |
| SCHEMBL12621477 | 0.80 | KDM4E (0.35) | KDM4EPOLA1TAS1R3TAS1R1STING1 | |
| SCHEMBL17037317 | 0.80 | STING1 (0.49) | STING1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159922-A1 | MODIFIED OLIGOMERIC COMPOUNDS AND USES THEREOF | IONIS PHARMACEUTICALS, INC. (US) | 2023-05-25 | — | — | US | disclosed |
| US-20230159922-A1 | MODIFIED OLIGOMERIC COMPOUNDS AND USES THEREOF | IONIS PHARMACEUTICALS, INC. (US) | 2023-05-25 | — | — | US | disclosed |
| EP-4013428-A1 | MODIFIED OLIGOMERIC COMPOUNDS AND USES THEREOF | Ionis Pharmaceuticals, Inc. (US) | 2022-06-22 | — | — | EP | disclosed |
| WO-2021030763-A1 | MODIFIED OLIGOMERIC COMPOUNDS AND USES THEREOF | IONIS PHARMACEUTICALS, INC. (US) | 2021-02-18 | — | — | WO | disclosed |