Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 11/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20774144 | 0.87 | TAAR1 (0.40) | STING1PDE3BPDE3ATAAR1ADORA3 | |
| SCHEMBL20774145 | 0.87 | TAAR1 (0.40) | STING1PDE3BPDE3ATAAR1ADORA3 | |
| SCHEMBL19949242 | 0.84 | ADORA3 (0.41) | PDE3AADORA3 | |
| SCHEMBL19953772 | 0.84 | ADORA3 (0.41) | PDE3AADORA3 | |
| SCHEMBL12729604 | 0.84 | STING1 (0.46) | STING1PDE3BPDE3A | |
| SCHEMBL8620596 | 0.84 | STING1 (0.46) | STING1PDE3BPDE3A | |
| SCHEMBL29603744 | 0.83 | HINT1 (0.40) | STING1PDE3BPDE3ATAAR1 | |
| SCHEMBL10239049 | 0.83 | ADORA2A (0.39) | STING1ADORA3 | |
| SCHEMBL22983981 | 0.81 | STING1 (0.60) | STING1PDE3BPDE3A | |
| SCHEMBL14946363 | 0.81 | STING1 (0.60) | STING1PDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11267844-B2 | Spirothietane nucleosides | JANSSEN PHARMACEUTICA NV (BE) | 2022-03-08 | — | — | US | disclosed |
| EP-3676276-B1 | SPIROTHIETANE NUCLEOSIDES | JANSSEN PHARMACEUTICA NV (BE) | 2021-12-08 | — | — | EP | disclosed |
| US-20210139524-A1 | SPIROTHIETANE NUCLEOSIDES | JANSSEN PHARMACEUTICA NV (BE) | 2021-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11267844-B2 | Spirothietane nucleosides | SAMHD1, SLC28A1, SLC28A2 | STING1 2029/4885PDE3B 482/4885PDE3A 347/4885 |
| US-20210139524-A1 | SPIROTHIETANE NUCLEOSIDES | SAMHD1, SLC28A1, SLC28A2 | STING1 2029/4885PDE3B 482/4885PDE3A 347/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.