Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.68 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.57 |
| ▸ | OXTR | P30559 | 2/20 | 0.57 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 6/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | STAT3 | P40763 | 1/20 | 0.50 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11031260 | 0.84 | HPGD (0.69) | HPGDALDH1A1AVPR2OXTRAVPR1A | |
| SCHEMBL15690050 | 0.83 | NOTUM (0.47) | HPGDALDH1A1AVPR2OXTRAVPR1A | |
| SCHEMBL3454628 | 0.82 | HPGD (0.68) | HPGDALDH1A1AVPR2OXTRAVPR1A | |
| SCHEMBL5783412 | 0.81 | HPGD (1.00) | HPGDALDH1A1AVPR2OXTRAVPR1A | |
| SCHEMBL31556814 | 0.81 | HPGD (1.00) | HPGDALDH1A1AVPR2OXTRAVPR1A | |
| SCHEMBL21348490 | 0.79 | HPGD (0.62) | HPGDALDH1A1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL980588 | 0.78 | NOTUM (0.67) | HPGDALDH1A1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL8614711 | 0.78 | ALDH1A1 (0.61) | HPGDALDH1A1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL31680509 | 0.76 | HPGD (0.90) | HPGDALDH1A1AVPR2OXTRAVPR1A | |
| SCHEMBL16494462 | 0.75 | HPGD (0.69) | HPGDALDH1A1RAB9AKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998050346-A2 | ACETAMIDE AND UREA DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THE TREATMENT OF CNS DISORDERS | SMITHKLINE BEECHAM PLC (GB) | 1998-11-12 | — | — | WO | disclosed |