Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 14/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 13/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 12/20 | 0.56 |
| ▸ | GBA1 | P04062 | 1/20 | 0.46 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3240531 | 0.88 | SLC6A2 (0.44) | SLC6A2SLC6A4SLC6A3G6PC1 | |
| SCHEMBL14855420 | 0.86 | G6PC1 (0.46) | SLC6A2SLC6A4SLC6A3G6PC1 | |
| SCHEMBL14855136 | 0.85 | G6PC1 (0.49) | SLC6A2SLC6A4SLC6A3G6PC1 | |
| SCHEMBL14855858 | 0.83 | G6PC1 (0.51) | SLC6A2SLC6A4SLC6A3G6PC1 | |
| SCHEMBL3238188 | 0.83 | G6PC1 (0.51) | SLC6A2SLC6A4SLC6A3G6PC1 | |
| SCHEMBL28169437 | 0.81 | MEN1 (0.41) | SLC6A2SLC6A4SLC6A3G6PC1 | |
| SCHEMBL2877349 | 0.78 | SLC6A2 (0.73) | SLC6A2SLC6A4SLC6A3GBA1 | |
| SCHEMBL3811903 | 0.77 | DCUN1D1 (0.58) | SLC6A2SLC6A4SLC6A3GBA1DCUN1D1 | |
| SCHEMBL13541717 | 0.76 | SLC6A4 (0.60) | SLC6A2SLC6A4SLC6A3GBA1KCNH2 | |
| Hydrochloric Acid SCHEMBL21410210 | 0.75 | DCUN1D1 (0.57) | SLC6A2SLC6A4SLC6A3GBA1DCUN1D1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0820444-A1 | 1-PHENYLPYRAZOLE-3-CARBOXAMIDES ACTING ON NEUROTENSIN RECEPTORS | SANOFI (FR) | 1998-01-28 | — | — | EP | claimed |
| EP-0820444-A1 | 1-PHENYLPYRAZOLE-3-CARBOXAMIDES ACTING ON NEUROTENSIN RECEPTORS | SANOFI (FR) | 1998-01-28 | — | — | EP | disclosed |