Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | G6PC1 | P35575 | 1/20 | 0.49 |
| ▸ | ADH1A | P07327 | 3/20 | 0.47 |
| ▸ | ADH1C | P00326 | 2/20 | 0.47 |
| ▸ | AGER | Q15109 | 3/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3238188 | 0.98 | G6PC1 (0.51) | G6PC1ADH1AADH1CAGERMTNR1A | |
| SCHEMBL14855858 | 0.98 | G6PC1 (0.51) | G6PC1ADH1AADH1CAGERMTNR1A | |
| SCHEMBL14855420 | 0.98 | G6PC1 (0.46) | G6PC1ADH1AADH1CAGERMTNR1A | |
| SCHEMBL3240531 | 0.93 | SLC6A2 (0.44) | G6PC1ADH1AADH1CAGERMTNR1A | |
| SCHEMBL19773700 | 0.88 | G6PC1 (0.40) | G6PC1ADH1AADH1CAGERMTNR1A | |
| SCHEMBL8620642 | 0.85 | SLC6A2 (0.56) | G6PC1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL28169437 | 0.85 | MEN1 (0.41) | G6PC1AGERMTNR1ASLC6A2SLC6A4 | |
| SCHEMBL22813618 | 0.84 | PKM (0.43) | SLC6A2SLC6A4SLC6A3MEN1KMT2A | |
| SCHEMBL21985921 | 0.83 | ALDH1A1 (0.39) | G6PC1AGERMTNR1AUSP2HPGD | |
| SCHEMBL1299875 | 0.81 | ADH1A (0.53) | G6PC1ADH1AADH1CUSP2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104926795-B | Substituted heteroaryl compound and combinations thereof and purposes | 广东东阳光药业有限公司 | 2017-11-10 | — | — | CN | disclosed |
| CN-104672250-B | Substituted heteroaryl compound and combinations thereof and purposes | 广东东阳光药业有限公司 | 2017-11-07 | — | — | CN | disclosed |
| CN-104974163-B | Substituted heteroaryl compound and combinations thereof and purposes | 广东东阳光药业有限公司 | 2017-11-07 | — | — | CN | disclosed |
| US-20130165446-A1 | BENZO-OR PYRIDO-IMIDAZOLE DERIVATIVE | HORIKOSHI, HIROYOSHI (CA) | 2013-06-27 | — | — | US | disclosed |
| EP-2581373-A1 | BENZO- OR PYRIDO-IMIDAZOLE DERIVATIVE | Fujita, Takashi (JP) | 2013-04-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130165446-A1 | BENZO-OR PYRIDO-IMIDAZOLE DERIVATIVE | PPARG, PPARA, PPARD | G6PC1 2696/4885ADH1A 1349/4885ADH1C 1360/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.