Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ST14 | Q9Y5Y6 | 8/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 7/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 7/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 7/20 | 0.46 |
| ▸ | F2 | P00734 | 6/20 | 0.46 |
| ▸ | MAOB | P27338 | 3/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | PLG | P00747 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8509724 | 0.91 | ST14 (0.49) | ST14PRSS1PRSS2PRSS3F2 | |
| SCHEMBL861872 | 0.88 | ST14 (0.42) | ST14PRSS1PRSS2PRSS3F2 | |
| SCHEMBL3803821 | 0.85 | ST14 (0.51) | ST14PRSS1PRSS2PRSS3F2 | |
| SCHEMBL861820 | 0.85 | ST14 (0.56) | ST14PRSS1PRSS2PRSS3F2 | |
| SCHEMBL851813 | 0.81 | ST14 (0.53) | ST14PRSS1PRSS2PRSS3F2 | |
| SCHEMBL861124 | 0.80 | NPC1 (0.45) | ST14PRSS1PRSS2PRSS3F2 | |
| SCHEMBL860100 | 0.80 | ST14 (0.43) | ST14PRSS1PRSS2PRSS3F2 | |
| SCHEMBL8509922 | 0.79 | ST14 (0.53) | ST14PRSS1PRSS2PRSS3F2 | |
| SCHEMBL851900 | 0.79 | ST14 (0.51) | ST14PRSS1PRSS2PRSS3F2 | |
| SCHEMBL851656 | 0.78 | ST14 (0.51) | ST14PRSS1PRSS2PRSS3F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2432556-A1 | PROTEASE INHIBITORS | Orion Corporation (FI) | 2012-03-28 | — | — | EP | disclosed |
| WO-2010133748-A1 | PROTEASE INHIBITORS | ORION CORPORATION (FI) | 2010-11-25 | — | — | WO | disclosed |