Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | NQO2 | P16083 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8620912 | 1.00 | NFE2L2 (0.41) | NFE2L2TRPA1APPFFAR1MAOB | |
| SCHEMBL8622912 | 0.91 | FFAR1 (0.43) | APPFFAR1 | |
| SCHEMBL8622908 | 0.91 | FFAR1 (0.43) | APPFFAR1 | |
| SCHEMBL25856442 | 0.89 | NFE2L2 (0.50) | NFE2L2TRPA1APPHSD11B1NQO2 | |
| SCHEMBL8618581 | 0.85 | GRM5 (0.35) | NFE2L2TRPA1FFAR1GRM5 | |
| SCHEMBL8618584 | 0.85 | GRM5 (0.35) | NFE2L2TRPA1FFAR1GRM5 | |
| SCHEMBL8617838 | 0.84 | NFE2L2 (0.40) | NFE2L2TRPA1FFAR1GRM5 | |
| SCHEMBL8621475 | 0.84 | FFAR1 (0.34) | NFE2L2FFAR1 | |
| SCHEMBL8621471 | 0.84 | FFAR1 (0.34) | NFE2L2FFAR1 | |
| SCHEMBL8617834 | 0.84 | NFE2L2 (0.40) | NFE2L2TRPA1FFAR1GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0648723-B1 | Diphenylacetylene compound, process for preparing the same and liquid crystal composition and element comprising the same | SUMITOMO CHEMICAL CO (JP) | 1998-05-20 | — | — | EP | disclosed |
| US-5658489-A | EXCELLENT ANISOTROPY OF REFRACTIVE INDEX; LOW VISCOSITY | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-08-19 | — | — | US | disclosed |
| EP-0648723-A1 | Diphenylacetylene compound, process for preparing the same and liquid crystal composition and element comprising the same | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1995-04-19 | — | — | EP | disclosed |