SCHEMBL8621471

SCHEMBL8621471

CCC/C=C/c1ccc(C#Cc2cc(F)c(F)c(F)c2)cc1

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 3/20 0.34
TUBB1 Q9H4B7 2/20 0.33
FFAR4 Q5NUL3 1/20 0.31
NFE2L2 Q16236 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8621475 1.00 FFAR1 (0.34) FFAR1TUBB1FFAR4NFE2L2
SCHEMBL8617834 0.88 NFE2L2 (0.40) FFAR1FFAR4NFE2L2
SCHEMBL8617838 0.88 NFE2L2 (0.40) FFAR1FFAR4NFE2L2
SCHEMBL8618571 0.86 TRPV4 (0.33) FFAR1
SCHEMBL8618576 0.86 TRPV4 (0.33) FFAR1
SCHEMBL8622912 0.85 FFAR1 (0.43) FFAR1
SCHEMBL8622908 0.85 FFAR1 (0.43) FFAR1
SCHEMBL8620908 0.84 NFE2L2 (0.41) FFAR1NFE2L2
SCHEMBL8620912 0.84 NFE2L2 (0.41) FFAR1NFE2L2
SCHEMBL8619086 0.83 FFAR1 (0.43) FFAR1FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0648723-B1 Diphenylacetylene compound, process for preparing the same and liquid crystal composition and element comprising the same SUMITOMO CHEMICAL CO (JP) 1998-05-20 EP disclosed
US-5658489-A EXCELLENT ANISOTROPY OF REFRACTIVE INDEX; LOW VISCOSITY SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-08-19 US disclosed
EP-0648723-A1 Diphenylacetylene compound, process for preparing the same and liquid crystal composition and element comprising the same SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1995-04-19 EP disclosed