Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | ICMT | O60725 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8855946 | 0.90 | ICMT (0.48) | MAPTPOLBICMTTHRBNPC1 | |
| SCHEMBL8626149 | 0.88 | MAPT (0.52) | MAPTPOLBICMTADRB2ADRB1 | |
| 4-Nitrobenzoic Acid SCHEMBL8645150 | 0.84 | MAPT (0.48) | MAPTPOLBICMTADRB2ADRB1 | |
| SCHEMBL6445161 | 0.83 | TRPV1 (0.47) | MAPTPOLBICMTCYP1A2CYP3A4 | |
| SCHEMBL8621087 | 0.80 | POLB (0.60) | MAPTPOLBICMTALDH1A1ADRB2 | |
| SCHEMBL8621095 | 0.80 | POLB (0.60) | MAPTPOLBICMTALDH1A1ADRB2 | |
| SCHEMBL8623311 | 0.80 | LMNA (0.53) | MAPTPOLBICMTALDH1A1THRB | |
| SCHEMBL8620646 | 0.79 | TRPV1 (0.42) | MAPTICMTADRB2ADRB1ADRB3 | |
| SCHEMBL8625198 | 0.79 | TRPV1 (0.46) | MAPTPOLBICMTCYP1A2CYP3A4 | |
| SCHEMBL8618525 | 0.78 | TRPV1 (0.50) | MAPTALDH1A1MEN1KMT2AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711749-B1 | Process for producing geranylgeraniol | KURARAY CO (JP) | 1998-05-20 | — | — | EP | disclosed |
| US-5663461-A | HYDROLYSIS OF ESTER | KURARAY CO., LTD. (JP) | 1997-09-02 | — | — | US | disclosed |
| EP-0711749-A1 | Process for producing geranylgeraniol | KURARAY CO., LTD. (JP) | 1996-05-15 | — | — | EP | disclosed |