Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 4/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5450319 | 0.81 | TSHR (0.61) | ALDH1A1TSHRCA1CA2CA9 | |
| SCHEMBL2703111 | 0.79 | ALDH1A1 (0.61) | ALDH1A1TSHRCA1CA2CA9 | |
| SCHEMBL6744925 | 0.79 | ALDH1A1 (0.61) | ALDH1A1TSHRCA1CA2CA9 | |
| SCHEMBL40436 | 0.78 | ALDH1A1 (0.59) | ALDH1A1TSHRCA1CA2CA9 | |
| SCHEMBL793986 | 0.78 | TSHR (0.56) | ALDH1A1TSHRCA1CA2CA9 | |
| SCHEMBL712779 | 0.78 | ALDH1A1 (0.59) | ALDH1A1TSHRTDP1MAPK1L3MBTL1 | |
| SCHEMBL28908802 | 0.78 | ALDH1A1 (0.59) | ALDH1A1TSHRCA1CA2CA9 | |
| SCHEMBL5720650 | 0.77 | TSHR (0.50) | ALDH1A1TSHRCA1CA2CA9 | |
| SCHEMBL18427393 | 0.76 | ALDH1A1 (0.68) | ALDH1A1TSHRCA1CA2CA9 | |
| SCHEMBL40338 | 0.76 | ALDH1A1 (0.68) | ALDH1A1TSHRCA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0664297-B1 | Use of cyclic Didepsipeptides having 12 ring atoms to control endoparasites, novel cyclic depsipeptides with 12 ring atoms and process for their synthesis | BAYER AG (DE) | 1998-04-08 | — | — | EP | disclosed |