Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | GRM5 | P41594 | 2/20 | 0.49 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14437516 | 0.88 | MAOB (0.64) | ALDH1A1NPC1MAOBRAB9AL3MBTL1 | |
| SCHEMBL30405517 | 0.86 | TSHR (0.50) | ALDH1A1TSHRNPC1MAPTGRM5 | |
| SCHEMBL19599654 | 0.86 | FFAR1 (0.51) | ALDH1A1MAOBSMN1; SMN2 | |
| SCHEMBL9622282 | 0.85 | NPC1 (0.52) | ALDH1A1TSHRNPC1MAPTGRM5 | |
| Acetone SCHEMBL28740549 | 0.85 | TSHR (0.71) | ALDH1A1TSHRNPC1MAOBRAB9A | |
| Acetic Acid SCHEMBL4466285 | 0.85 | TSHR (0.71) | ALDH1A1TSHRNPC1MAOBRAB9A | |
| Acetic Acid SCHEMBL28710458 | 0.85 | TSHR (0.71) | ALDH1A1TSHRNPC1MAOBRAB9A | |
| Acetic Acid SCHEMBL28567289 | 0.84 | ALDH1A1 (0.55) | ALDH1A1TSHRNPC1MAPTGRM5 | |
| SCHEMBL28610357 | 0.83 | ALDH1A1 (0.46) | ALDH1A1TSHRNPC1MAPTKMT2A | |
| SCHEMBL231282 | 0.83 | TSHR (0.61) | ALDH1A1TSHRNPC1MAPTGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 207 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006052310-A2 | NICKEL ELECTROPLATING BATH DESIGNED TO REPLACE MONOVALENT COPPER STRIKE SOLUTIONS | MACDERMID, INCORPORATED (US) | 2006-05-18 | — | — | WO | claimed |
| US-20060096868-A1 | Nickel electroplating bath designed to replace monovalent copper strike solutions | MACDERMID, INCORPORATED | 2006-05-11 | — | — | US | claimed |
| EP-4688717-A1 | PALLADIUM-CATALYZED CHEMOSELECTIVE MONO-ALPHA-ARYLATION OF O-PROTECTED HYDROXYACETONE | Bayer Aktiengesellschaft (DE) | 2026-02-11 | — | — | EP | disclosed |
| US-20250316750-A1 | MODIFIED SULFIDE SOLID ELECTROLYTE, PRODUCTION METHOD FOR SAME, ELECTRODE MIXTURE, AND LITHIUM-ION BATTERY | IDEMITSU KOSAN CO.,LTD. (JP) | 2025-10-09 | — | — | US | disclosed |
| US-12324802-B2 | Modulators of cystic fibrosis transmembrane conductance regulator | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2025-06-10 | — | — | US | disclosed |
| US-20250163047-A1 | HETEROCYCLIC COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH | BEIGENE, LTD. (KY) | 2025-05-22 | — | — | US | disclosed |
| CN-119547157-A | Modified sulfide solid electrolyte, manufacturing method thereof, electrode composite material and lithium ion battery | 出光兴产株式会社 | 2025-02-28 | — | — | CN | disclosed |
| EP-4476219-A1 | HETEROCYCLIC COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH | BeiGene, Ltd. (KY) | 2024-12-18 | — | — | EP | disclosed |
| WO-2024200462-A1 | PALLADIUM-CATALYZED CHEMOSELECTIVE MONO-α-ARYLATION OF O-PROTECTED HYDROXYACETONE | BAYER AKTIENGESELLSCHAFT (DE) | 2024-10-03 | — | — | WO | disclosed |
| CN-118696043-A | Heterocyclic compounds, compositions thereof and methods of treatment therewith | 百济神州有限公司 | 2024-09-24 | — | — | CN | disclosed |
| WO-2024024824-A1 | MODIFIED SULFIDE SOLID ELECTROLYTE, PRODUCTION METHOD FOR SAME, ELECTRODE MIXTURE, AND LITHIUM-ION BATTERY | 出光興産株式会社 | 2024-02-01 | — | — | WO | disclosed |
| US-5817776-A | TECHNETIUM 99 COMPLEXES, SINGLE PHOTON EMISSION TOMOGRAPHY | EMORY UNIVERSITY (US) | 1998-10-06 | — | — | US | disclosed |
| US-5808146-A | Amino acid analogs for tumor imaging | EMORY UNIVERSITY (US) | 1998-09-15 | — | — | US | disclosed |
| EP-0862464-A1 | AMINO ACID ANALOGS FOR TUMOR IMAGING | EMORY UNIVERSITY (US) | 1998-09-09 | — | — | EP | disclosed |
| EP-0437290-B1 | Process for the preparation of 5-oxohexane nitriles and the compound 2,4-dimethyl-5-oxohexane nitrile | DSM NV (NL) | 1998-05-06 | — | — | EP | disclosed |
| WO-1997017092-A1 | AMINO ACID ANALOGS FOR TUMOR IMAGING | EMORY UNIVERSITY (US) | 1997-05-15 | — | — | WO | disclosed |
| US-5334721-A | Reacting a methyl ketone and an alpha,beta-unsaturated nitrile in the presence of a basic catalyst; preparation of a 2-methyl-3,5-dialkylpyridine; cyclization; dehydrogenation | STAMICARBON B.V. (NL) | 1994-08-02 | — | — | US | disclosed |
| US-5254712-A | Using basic catalyst | STAMICARBON B.V. (NL) | 1993-10-19 | — | — | US | disclosed |
| EP-0437290-A1 | Process for the preparation of 5-oxohexane nitriles and the compound 2,4-dimethyl-5-oxohexane nitrile | DSM N.V. (NL) | 1991-07-17 | — | — | EP | disclosed |
| US-4400316-A | POLYPEPTIDES | TOYO JOZO KABUSHIKI KAISHA (JP) | 1983-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250163047-A1 | HETEROCYCLIC COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH | NFATC1, GZMB, IFNG | ALDH1A1 1242/4885TSHR 3786/4885NPC1 1714/4885 |
| US-12324802-B2 | Modulators of cystic fibrosis transmembrane conductance regulator | CFTR, SCNN1G, SCNN1B | ALDH1A1 3972/4885TSHR 2157/4885NPC1 271/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.