Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 4/20 | 0.50 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.49 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.35 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.35 |
| ▸ | EP300 | Q09472 | 6/20 | 0.34 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.34 |
| ▸ | ALB | P02768 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.34 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.34 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.34 |
| ▸ | NT5E | P21589 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL140792 | 0.88 | FGFR1 (0.50) | FGFR1SLC22A6PDE3APDE4DSLC29A1 | |
| SCHEMBL18069556 | 0.88 | FGFR1 (0.50) | FGFR1SLC22A6PDE3APDE4DSLC29A1 | |
| SCHEMBL24420123 | 0.86 | FGFR1 (0.58) | FGFR1SLC22A6PDE3APDE4DSLC29A1 | |
| SCHEMBL155990 | 0.86 | FGFR1 (0.58) | FGFR1SLC22A6PDE3APDE4DSLC29A1 | |
| SCHEMBL254930 | 0.86 | FGFR1 (0.58) | FGFR1SLC22A6PDE3APDE4DSLC29A1 | |
| SCHEMBL7269776 | 0.81 | FGFR1 (0.52) | FGFR1SLC22A6PDE3APDE4DSLC29A1 | |
| SCHEMBL7269771 | 0.81 | FGFR1 (0.52) | FGFR1SLC22A6PDE3APDE4DSLC29A1 | |
| SCHEMBL17372300 | 0.78 | FGFR1 (0.44) | FGFR1SLC22A6PDE3APDE4DSLC29A1 | |
| SCHEMBL5180818 | 0.77 | FGFR1 (0.55) | FGFR1SLC22A6PDE3APDE4DSLC29A1 | |
| SCHEMBL12652844 | 0.77 | FGFR1 (0.51) | FGFR1SLC22A6PDE3APDE4DLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5733896-A | VIRICIDE FOR RETROVIRUS | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) | 1998-03-31 | — | — | US | disclosed |
| EP-0454427-B1 | Antiretroviral bases | ACAD OF SCIENCE CZECH REPUBLIC (CZ) | 1995-12-06 | — | — | EP | disclosed |
| EP-0454427-A1 | Antiretroviral bases | Institute of Organic Chemistry and Biochemistry of the Academy of Sciences of the Czech Republic (CZ) | 1991-10-30 | — | — | EP | disclosed |