Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 5/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8616424 | 0.89 | MAPT (0.41) | MAPTHPGDALDH1A1LMNAATM | |
| SCHEMBL8623631 | 0.81 | MAPT (0.43) | MAPTHPGDALDH1A1LMNAATM | |
| SCHEMBL8622969 | 0.78 | MAPT (0.44) | MAPTHPGDALDH1A1LMNAATM | |
| SCHEMBL8618857 | 0.78 | MAPT (0.44) | MAPTHPGDALDH1A1LMNAATM | |
| SCHEMBL8621708 | 0.78 | MAPT (0.50) | MAPTHPGDALDH1A1LMNAATM | |
| SCHEMBL8619763 | 0.78 | CA2 (0.40) | MAPTHPGDALDH1A1LMNAATM | |
| SCHEMBL9029547 | 0.77 | MAPT (0.68) | MAPTHPGDALDH1A1LMNAATM | |
| SCHEMBL8621433 | 0.75 | MAPT (0.42) | MAPTHPGDALDH1A1LMNAATM | |
| SCHEMBL8621394 | 0.75 | KDM4E (0.50) | MAPTHPGDALDH1A1LMNAATM | |
| SCHEMBL8609188 | 0.75 | MAPT (0.58) | MAPTHPGDALDH1A1LMNAATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5710138-A | Benzo f!quinoxalinedione derivatives, their production and use in pharmaceutical agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-01-20 | — | — | US | disclosed |