Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | GRM6 | O15303 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.43 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.43 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.43 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.43 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8617957 | 0.93 | MAPT (0.43) | MAPTHPGDKMT2AALDH1A1TDP1 | |
| SCHEMBL8619763 | 0.87 | CA2 (0.40) | MAPTHPGDKMT2AALDH1A1TDP1 | |
| SCHEMBL9038291 | 0.86 | CA12 (0.41) | MAPTHPGDKMT2AALDH1A1TDP1 | |
| SCHEMBL8618700 | 0.83 | MAPT (0.45) | MAPTHPGDKMT2AALDH1A1TDP1 | |
| SCHEMBL8619762 | 0.82 | CA12 (0.46) | MAPTHPGDKMT2AALDH1A1TDP1 | |
| SCHEMBL8623637 | 0.82 | MAPT (0.40) | MAPTHPGDKMT2AALDH1A1TDP1 | |
| SCHEMBL8621704 | 0.81 | MAPT (0.52) | MAPTHPGDKMT2AALDH1A1TDP1 | |
| SCHEMBL8616761 | 0.79 | CA12 (0.50) | MAPTHPGDKMT2AALDH1A1TDP1 | |
| SCHEMBL9037445 | 0.79 | CA12 (0.42) | MAPTHPGDKMT2AALDH1A1TDP1 | |
| SCHEMBL8620831 | 0.77 | CA12 (0.46) | MAPTHPGDKMT2AALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5710138-A | Benzo f!quinoxalinedione derivatives, their production and use in pharmaceutical agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-01-20 | — | — | US | disclosed |