Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | FBP1 | P09467 | 6/20 | 0.39 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.36 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.36 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.36 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | USP5 | P45974 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.34 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.34 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8807743 | 0.86 | SIRT2 (0.41) | SIRT2PARP1FBP1GRIA1GRIA2 | |
| SCHEMBL8617919 | 0.83 | SIRT2 (0.43) | SIRT2PARP1FBP1GRIA1GRIA2 | |
| SCHEMBL8621659 | 0.82 | SIRT2 (0.43) | SIRT2PARP1FBP1GRIA1GRIA2 | |
| Bicarbonate SCHEMBL8807164 | 0.81 | SIRT2 (0.47) | SIRT2PARP1FBP1KDM4EMEN1 | |
| SCHEMBL8619552 | 0.80 | SIRT2 (0.41) | SIRT2PARP1FBP1MEN1KMT2A | |
| SCHEMBL8622360 | 0.79 | SIRT2 (0.40) | SIRT2PARP1FBP1KDM4EALDH1A1 | |
| SCHEMBL8623646 | 0.77 | GRIK1 (0.54) | SIRT2PARP1GRIA1GRIA2GRIA3 | |
| SCHEMBL8620025 | 0.77 | SIRT2 (0.39) | SIRT2PARP1FBP1GRIA1GRIA2 | |
| SCHEMBL8617993 | 0.77 | SIRT2 (0.39) | SIRT2PARP1FBP1KDM4EMEN1 | |
| SCHEMBL8620034 | 0.76 | SIRT2 (0.38) | SIRT2PARP1FBP1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5710138-A | Benzo f!quinoxalinedione derivatives, their production and use in pharmaceutical agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-01-20 | — | — | US | claimed |
| EP-0696289-B1 | BENZO[F]QUINOXALINDIONE DERIVATIVES, THEIR PREPARATION AND THEIR USE IN DRUGS | SCHERING AG (DE) | 1997-03-12 | — | — | EP | claimed |
| US-5710138-A | Benzo f!quinoxalinedione derivatives, their production and use in pharmaceutical agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-01-20 | — | — | US | disclosed |