Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 10/20 | 0.49 |
| ▸ | DRD2 | P14416 | 9/20 | 0.49 |
| ▸ | DRD3 | P35462 | 7/20 | 0.49 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTR1B | P28222 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23398174 | 0.83 | CHRM2 (0.46) | CHRM2CD274 | |
| SCHEMBL7391666 | 0.76 | DRD4 (0.50) | DRD4DRD2DRD3KCNA3KDM4E | |
| SCHEMBL11895289 | 0.75 | DRD2 (0.83) | DRD4DRD2DRD3KCNA3HDAC3 | |
| SCHEMBL9265562 | 0.73 | DRD4 (0.72) | DRD4DRD2DRD3CHRM2KDM4E | |
| SCHEMBL11894925 | 0.73 | DRD2 (0.80) | DRD4DRD2DRD3KCNA3HDAC3 | |
| Hydrochloric Acid SCHEMBL8055001 | 0.72 | DRD4 (0.79) | DRD4DRD2DRD3HTR1B | |
| SCHEMBL6507898 | 0.72 | HDAC1 (0.56) | DRD4DRD2DRD3HDAC3HDAC4 | |
| SCHEMBL7395717 | 0.71 | HTR1A (0.46) | DRD4DRD2DRD3CHRM2KDM4E | |
| SCHEMBL10133077 | 0.71 | GAA (0.51) | DRD4CHRM2 | |
| SCHEMBL10476759 | 0.69 | DRD4 (0.95) | DRD4DRD2DRD3KCNA3HTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5767132-A | CENTRAL NERVOUS SYSTEM | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-06-16 | — | — | US | disclosed |