Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | ABCB1 | P08183 | 17/20 | 0.55 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.52 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5359695 | 1.00 | CYP3A4 (0.59) | CYP3A4MAPK1ABCB1ABCC1ABCG2 | |
| SCHEMBL3805652 | 0.93 | CYP3A4 (0.59) | CYP3A4MAPK1ABCB1 | |
| SCHEMBL862428 | 0.89 | MMP2 (0.53) | — | |
| SCHEMBL14691188 | 0.87 | CYP3A4 (0.78) | CYP3A4MAPK1ABCB1 | |
| SCHEMBL3805650 | 0.87 | CYP3A4 (0.78) | CYP3A4MAPK1ABCB1 | |
| SCHEMBL862196 | 0.85 | MMP2 (0.61) | CYP3A4MAPK1 | |
| SCHEMBL862107 | 0.83 | MMP2 (0.59) | CYP3A4MAPK1 | |
| SCHEMBL862370 | 0.82 | MMP2 (0.61) | CYP3A4MAPK1 | |
| SCHEMBL862195 | 0.80 | CYP3A4 (0.67) | CYP3A4MAPK1ABCB1 | |
| SCHEMBL25246785 | 0.80 | CYP3A4 (0.78) | CYP3A4MAPK1ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143308-B2 | Synthesis of oligo/poly(catechins) and methods of use | UNIVERSITY OF MASSACHUSETTS LOWELL (US) | 2012-03-27 | — | — | US | disclosed |
| US-20090170928-A1 | Synthesis of oligo/poly(catechins) and methods of use | GOVERNMENT OF THE UNITED STATES | 2009-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090170928-A1 | Synthesis of oligo/poly(catechins) and methods of use | POLI, PUF60, FABP3 | CYP3A4 1162/4885MAPK1 1507/4885ABCB1 1873/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.